Effect of indomethacin in postoperative pain when used as an irrigant: An in vivo randomized control trial

Aim: The aim of the study was to evaluate the effect of indomethacin in postoperative pain when used as an irrigant. Methods: Sixty patients fulfilling the criteria to undergo root canal treatment were randomly divided into two groups. Group 1 consisted of routine irrigation regimen, whereas Group 2...

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Bibliographic Details
Main Authors: Shailendra Mashalkar, Apoorva Suresh, Kuchi Keerthi, Rutika Naik, Syed Mubeen Mohiuddin Hussaini, Manisha Rani Bharathi
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2025-01-01
Series:Endodontology
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Online Access:https://journals.lww.com/10.4103/endo.endo_89_24
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Summary:Aim: The aim of the study was to evaluate the effect of indomethacin in postoperative pain when used as an irrigant. Methods: Sixty patients fulfilling the criteria to undergo root canal treatment were randomly divided into two groups. Group 1 consisted of routine irrigation regimen, whereas Group 2 consisted of routine irrigants and 1% indomethacin. Pain levels before root canal treatment were documented for all the patients utilizing a Visual Analog Scale (VAS). Irrigation protocol was followed as mentioned above for the respective groups. Postoperative pain was recorded after 24, 48, and 72 h for all the patients using VAS. Pain scores were examined with Shapiro–Wilk test and P < 0.05 was considered statistically significant. Results: Group 2 demonstrated a significant drop in postoperative pain. Conclusion: It was observed that there was a noteworthy reduction in postoperative pain when indomethacin was used as an irrigant.
ISSN:0970-7212
2543-0831