Consumption of dopamine receptor 1 agonist SKF-38393 reduces constant-light-induced hyperactivity, depression-like, and anxiety-like behaviors in a sex specific manner in C57BL/6J mice

Consumption of dopamine receptor 1 agonist SKF-38393 reduces constant-light-induced hyperactivity, depression-like, and anxiety-like behaviors in a sex specific manner in C57BL/6J mice

Artificial light exposure during nighttime, including constant light (LL), is an increasingly prevalent environmental occurrence linked to impaired mood and cognitive impairments in both humans and animal models. Dopamine and dopamine 1 receptors are well known to modulate circadian rhythms and mood...

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Bibliographic Details
Main Authors: Grace E. Guindon, Alexis Anzalone, Samantha G. Burke, Cloey A. Murphy, Maria E. Milano, John C. Price, Stephanie Tadros, Alexander T. McFarland, Fernanda Medieros Contini, Joseph A. Seggio
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-03-01
Series:Frontiers in Behavioral Neuroscience
Subjects:
light
circadian rhythm
anhedonia
dopamine
open field (OF)
mouse behavior
Online Access:https://www.frontiersin.org/articles/10.3389/fnbeh.2025.1537048/full
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