EPLIN, a prospective oncogenic molecule with contribution to growth, migration and drug resistance in pancreatic cancer

EPLIN, a prospective oncogenic molecule with contribution to growth, migration and drug resistance in pancreatic cancer

Abstract Most pancreatic cancer patients are diagnosed at advanced stages, with poor survival rates and drug resistance making pancreatic cancer one of the highest causes of cancer death in the UK. Understanding the underlying mechanism behind its carcinogenesis, metastasis and drug resistance has b...

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Bibliographic Details
Main Authors: Jianyuan Zeng, Cai Wang, Fiona Ruge, Edison Ke Ji, Tracey A. Martin, Andrew J. Sanders, Shuqin Jia, Chunyi Hao, Wen G. Jiang
Format: Article
Language:English
Published: Nature Portfolio 2024-12-01
Series:Scientific Reports
Subjects:
EPLIN
Migration
Pancreatic cancer
PIK3s
MAPK
Chemotherapeutic resistance
Online Access:https://doi.org/10.1038/s41598-024-81485-w
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