Structural insights into the initiation of free radical formation in the Class Ib ribonucleotide reductases in Mycobacteria
Class I ribonucleotide reductases consisting of α and β subunits convert ribonucleoside diphosphates to deoxyribonucleoside diphosphates involving an intricate free radical mechanism. The generation of free radicals in the Class Ib ribonucleotide reductases is mediated by di-manganese ions in the β...
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| Main Authors: | Lumbini R. Yadav, Vasudha Sharma, Maheswaran Shanmugam, Shekhar C. Mande |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2024-01-01
|
| Series: | Current Research in Structural Biology |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2665928X24000345 |
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