An IS element-driven antisense RNA attenuates the expression of serotype 2 fimbriae and the cytotoxicity of Bordetella pertussis

Insertion sequences (IS) represent mobile genetic elements that have been shown to be associated with bacterial evolution and adaptation due to their effects on genome plasticity. In Bordetella pertussis, the causative agent of whooping cough, the numerous IS elements induce genomic rearrangements a...

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Bibliographic Details
Main Authors:	Alexandre D’Halluin, Denisa Petráčková, Ivana Čurnová, Jakub Držmíšek, Jan Čapek, Peggy Bouquet, Loïc Henin, Rudy Antoine, Loïc Coutte, Camille Locht, Branislav Večerek, David Hot
Format:	Article
Language:	English
Published:	Taylor & Francis Group 2025-12-01
Series:	Emerging Microbes and Infections
Subjects:	Bordetella pertussis antisense RNA insertion sequence fimbriae serotype 2 modulation of virulence cytotoxicity towards macrophages
Online Access:	https://www.tandfonline.com/doi/10.1080/22221751.2025.2451718
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An IS element-driven antisense RNA attenuates the expression of serotype 2 fimbriae and the cytotoxicity of Bordetella pertussis

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