Influenza A virus in dairy cattle: infection biology and potential mammary gland-targeted vaccines
Abstract Influenza, a major “One Health” threat, has gained heightened attention following recent reports of highly pathogenic avian influenza in dairy cattle and cow-to-human transmission in the USA. This review explores general aspects of influenza A virus (IAV) biology, its interactions with mamm...
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| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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Nature Portfolio
2025-01-01
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| Series: | npj Vaccines |
| Online Access: | https://doi.org/10.1038/s41541-025-01063-7 |
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| _version_ | 1832594977893384192 |
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| author | Rodrigo Prado Martins Daniel Marc Pierre Germon Sascha Trapp Ignacio Caballero-Posadas |
| author_facet | Rodrigo Prado Martins Daniel Marc Pierre Germon Sascha Trapp Ignacio Caballero-Posadas |
| author_sort | Rodrigo Prado Martins |
| collection | DOAJ |
| description | Abstract Influenza, a major “One Health” threat, has gained heightened attention following recent reports of highly pathogenic avian influenza in dairy cattle and cow-to-human transmission in the USA. This review explores general aspects of influenza A virus (IAV) biology, its interactions with mammalian hosts, and discusses the key considerations for developing vaccines to prevent or curtail IAV infection in the bovine mammary gland and its spread through milk. |
| format | Article |
| id | doaj-art-70c1328e68ae41ada2c4e82a5f4addb6 |
| institution | Kabale University |
| issn | 2059-0105 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | npj Vaccines |
| spelling | doaj-art-70c1328e68ae41ada2c4e82a5f4addb62025-01-19T12:09:18ZengNature Portfolionpj Vaccines2059-01052025-01-011011910.1038/s41541-025-01063-7Influenza A virus in dairy cattle: infection biology and potential mammary gland-targeted vaccinesRodrigo Prado Martins0Daniel Marc1Pierre Germon2Sascha Trapp3Ignacio Caballero-Posadas4PFIE, INRAEISP, INRAE, Université de ToursISP, INRAE, Université de ToursISP, INRAE, Université de ToursISP, INRAE, Université de ToursAbstract Influenza, a major “One Health” threat, has gained heightened attention following recent reports of highly pathogenic avian influenza in dairy cattle and cow-to-human transmission in the USA. This review explores general aspects of influenza A virus (IAV) biology, its interactions with mammalian hosts, and discusses the key considerations for developing vaccines to prevent or curtail IAV infection in the bovine mammary gland and its spread through milk.https://doi.org/10.1038/s41541-025-01063-7 |
| spellingShingle | Rodrigo Prado Martins Daniel Marc Pierre Germon Sascha Trapp Ignacio Caballero-Posadas Influenza A virus in dairy cattle: infection biology and potential mammary gland-targeted vaccines npj Vaccines |
| title | Influenza A virus in dairy cattle: infection biology and potential mammary gland-targeted vaccines |
| title_full | Influenza A virus in dairy cattle: infection biology and potential mammary gland-targeted vaccines |
| title_fullStr | Influenza A virus in dairy cattle: infection biology and potential mammary gland-targeted vaccines |
| title_full_unstemmed | Influenza A virus in dairy cattle: infection biology and potential mammary gland-targeted vaccines |
| title_short | Influenza A virus in dairy cattle: infection biology and potential mammary gland-targeted vaccines |
| title_sort | influenza a virus in dairy cattle infection biology and potential mammary gland targeted vaccines |
| url | https://doi.org/10.1038/s41541-025-01063-7 |
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