Coccidioidomycosis of the Vocal Cords Presenting in Sepsis: A Case Report and Literature Review

Coccidioidomycosis is a predominantly pulmonary disease caused by species of Coccidioides, a fungus endemic to the American Southwest. Most cases involve exclusively pulmonary manifestations while less than one percent present with disseminated infection, usually with meningeal or skin involvement....

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Main Authors: Curtis Converse, Atish Dey, Samuel Decker, Sarkis Arabian, Michael Neeki
Format: Article
Language:English
Published: Wiley 2020-01-01
Series:Case Reports in Critical Care
Online Access:http://dx.doi.org/10.1155/2020/8025391
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author Curtis Converse
Atish Dey
Samuel Decker
Sarkis Arabian
Michael Neeki
author_facet Curtis Converse
Atish Dey
Samuel Decker
Sarkis Arabian
Michael Neeki
author_sort Curtis Converse
collection DOAJ
description Coccidioidomycosis is a predominantly pulmonary disease caused by species of Coccidioides, a fungus endemic to the American Southwest. Most cases involve exclusively pulmonary manifestations while less than one percent present with disseminated infection, usually with meningeal or skin involvement. In this case, a patient with a history of odynophagia, sore throat, productive cough, weight loss, and abnormalities on chest radiograph presented with sepsis and diabetic ketoacidosis. During admission, the patient underwent bronchoscopy with resulting tissue and bronchoalveolar lavage samples positive for Coccidioides immitis, later supported by confirmatory serum studies. This case illustrates a rare presentation of vocal fold involvement without direct invasion from a continuous site and highlights the importance of a high index of suspicion for disseminated coccidioidomycosis with prompt antifungal treatment in order to avoid the very high morbidity and mortality in such cases.
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institution Kabale University
issn 2090-6420
2090-6439
language English
publishDate 2020-01-01
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series Case Reports in Critical Care
spelling doaj-art-70bfbc973d2f4318a4f943aa1832c5fa2025-02-03T05:49:55ZengWileyCase Reports in Critical Care2090-64202090-64392020-01-01202010.1155/2020/80253918025391Coccidioidomycosis of the Vocal Cords Presenting in Sepsis: A Case Report and Literature ReviewCurtis Converse0Atish Dey1Samuel Decker2Sarkis Arabian3Michael Neeki4Department of Internal Medicine, Arrowhead Regional Medical Center, Colton, CA, USADepartment of Internal Medicine, Arrowhead Regional Medical Center, Colton, CA, USADepartment of Emergency Medicine, Arrowhead Regional Medical Center, Colton, CA, USADepartment of Internal Medicine, Arrowhead Regional Medical Center, Colton, CA, USADepartment of Emergency Medicine, Arrowhead Regional Medical Center, Colton, CA, USACoccidioidomycosis is a predominantly pulmonary disease caused by species of Coccidioides, a fungus endemic to the American Southwest. Most cases involve exclusively pulmonary manifestations while less than one percent present with disseminated infection, usually with meningeal or skin involvement. In this case, a patient with a history of odynophagia, sore throat, productive cough, weight loss, and abnormalities on chest radiograph presented with sepsis and diabetic ketoacidosis. During admission, the patient underwent bronchoscopy with resulting tissue and bronchoalveolar lavage samples positive for Coccidioides immitis, later supported by confirmatory serum studies. This case illustrates a rare presentation of vocal fold involvement without direct invasion from a continuous site and highlights the importance of a high index of suspicion for disseminated coccidioidomycosis with prompt antifungal treatment in order to avoid the very high morbidity and mortality in such cases.http://dx.doi.org/10.1155/2020/8025391
spellingShingle Curtis Converse
Atish Dey
Samuel Decker
Sarkis Arabian
Michael Neeki
Coccidioidomycosis of the Vocal Cords Presenting in Sepsis: A Case Report and Literature Review
Case Reports in Critical Care
title Coccidioidomycosis of the Vocal Cords Presenting in Sepsis: A Case Report and Literature Review
title_full Coccidioidomycosis of the Vocal Cords Presenting in Sepsis: A Case Report and Literature Review
title_fullStr Coccidioidomycosis of the Vocal Cords Presenting in Sepsis: A Case Report and Literature Review
title_full_unstemmed Coccidioidomycosis of the Vocal Cords Presenting in Sepsis: A Case Report and Literature Review
title_short Coccidioidomycosis of the Vocal Cords Presenting in Sepsis: A Case Report and Literature Review
title_sort coccidioidomycosis of the vocal cords presenting in sepsis a case report and literature review
url http://dx.doi.org/10.1155/2020/8025391
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AT samueldecker coccidioidomycosisofthevocalcordspresentinginsepsisacasereportandliteraturereview
AT sarkisarabian coccidioidomycosisofthevocalcordspresentinginsepsisacasereportandliteraturereview
AT michaelneeki coccidioidomycosisofthevocalcordspresentinginsepsisacasereportandliteraturereview