Epidural abscess formation after chemotherapy for breast cancer: a case report and literature review

IntroductionSpinal epidural abscess is a rare infectious lesion of the central nervous system. Here, we report a rare case of a thoracic suppurative epidural abscess in a female patient who developed incomplete paralysis of both lower limbs after chemotherapy for breast cancer. She underwent surgery...

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Main Authors: Youzhi An, Lili Li, Qingning Liu, Zhen Zhang, Xuelin Lin
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Surgery
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fsurg.2025.1388278/full
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author Youzhi An
Lili Li
Qingning Liu
Zhen Zhang
Xuelin Lin
author_facet Youzhi An
Lili Li
Qingning Liu
Zhen Zhang
Xuelin Lin
author_sort Youzhi An
collection DOAJ
description IntroductionSpinal epidural abscess is a rare infectious lesion of the central nervous system. Here, we report a rare case of a thoracic suppurative epidural abscess in a female patient who developed incomplete paralysis of both lower limbs after chemotherapy for breast cancer. She underwent surgery and recovered well after surgery.Case reportA 49-year-old female patient developed an epidural abscess after chemotherapy for breast cancer; she suffered sudden pain and paralysis in both lower limbs. Thoracic T9–T11 laminectomy, abscess removal, bone grafting, fusion, and internal fixation were performed. After the operation, the muscle strength in both lower limbs gradually recovered.DiscussionThis is the first reported case of an epidural abscess after chemotherapy for breast cancer. The disease progresses rapidly. During the literature review process, we found that timely removal of the epidural abscess, combined with the administration of appropriate antibiotics at the same time, is crucial for improved healing and successful treatment.
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publisher Frontiers Media S.A.
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series Frontiers in Surgery
spelling doaj-art-70b35bdd2a354aeab4f75ed9433d66532025-01-23T06:56:02ZengFrontiers Media S.A.Frontiers in Surgery2296-875X2025-01-011210.3389/fsurg.2025.13882781388278Epidural abscess formation after chemotherapy for breast cancer: a case report and literature reviewYouzhi An0Lili Li1Qingning Liu2Zhen Zhang3Xuelin Lin4Second Department of Spinal Surgery, The Second People’s Hospital of Liaocheng, The Second Hospital of Liaocheng Affiliated to Shandong First Medical University, Linqing, Shandong, ChinaMedical Oncology, The Second People’s Hospital of Liaocheng, The Second Hospital of Liaocheng Affiliated to Shandong First Medical University, Linqing, Shandong, ChinaSecond Department of Spinal Surgery, The Second People’s Hospital of Liaocheng, The Second Hospital of Liaocheng Affiliated to Shandong First Medical University, Linqing, Shandong, ChinaSecond Department of Spinal Surgery, The Second People’s Hospital of Liaocheng, The Second Hospital of Liaocheng Affiliated to Shandong First Medical University, Linqing, Shandong, ChinaSecond Department of Spinal Surgery, The Second People’s Hospital of Liaocheng, The Second Hospital of Liaocheng Affiliated to Shandong First Medical University, Linqing, Shandong, ChinaIntroductionSpinal epidural abscess is a rare infectious lesion of the central nervous system. Here, we report a rare case of a thoracic suppurative epidural abscess in a female patient who developed incomplete paralysis of both lower limbs after chemotherapy for breast cancer. She underwent surgery and recovered well after surgery.Case reportA 49-year-old female patient developed an epidural abscess after chemotherapy for breast cancer; she suffered sudden pain and paralysis in both lower limbs. Thoracic T9–T11 laminectomy, abscess removal, bone grafting, fusion, and internal fixation were performed. After the operation, the muscle strength in both lower limbs gradually recovered.DiscussionThis is the first reported case of an epidural abscess after chemotherapy for breast cancer. The disease progresses rapidly. During the literature review process, we found that timely removal of the epidural abscess, combined with the administration of appropriate antibiotics at the same time, is crucial for improved healing and successful treatment.https://www.frontiersin.org/articles/10.3389/fsurg.2025.1388278/fullepidural abscesscase reportbreast cancerchemotherapycomplication
spellingShingle Youzhi An
Lili Li
Qingning Liu
Zhen Zhang
Xuelin Lin
Epidural abscess formation after chemotherapy for breast cancer: a case report and literature review
Frontiers in Surgery
epidural abscess
case report
breast cancer
chemotherapy
complication
title Epidural abscess formation after chemotherapy for breast cancer: a case report and literature review
title_full Epidural abscess formation after chemotherapy for breast cancer: a case report and literature review
title_fullStr Epidural abscess formation after chemotherapy for breast cancer: a case report and literature review
title_full_unstemmed Epidural abscess formation after chemotherapy for breast cancer: a case report and literature review
title_short Epidural abscess formation after chemotherapy for breast cancer: a case report and literature review
title_sort epidural abscess formation after chemotherapy for breast cancer a case report and literature review
topic epidural abscess
case report
breast cancer
chemotherapy
complication
url https://www.frontiersin.org/articles/10.3389/fsurg.2025.1388278/full
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AT qingningliu epiduralabscessformationafterchemotherapyforbreastcanceracasereportandliteraturereview
AT zhenzhang epiduralabscessformationafterchemotherapyforbreastcanceracasereportandliteraturereview
AT xuelinlin epiduralabscessformationafterchemotherapyforbreastcanceracasereportandliteraturereview