A2-Astrocyte Activation by Short-Term Hypoxia Rescues α-Synuclein Pre-Formed-Fibril-Induced Neuronal Cell Death

A2-Astrocyte Activation by Short-Term Hypoxia Rescues α-Synuclein Pre-Formed-Fibril-Induced Neuronal Cell Death

<b>Background/Objectives:</b> Parkinson’s disease (PD) is a neuro-degenerative disease for which a radical cure is not available, only symptomatic control. Studies have shown that hypoxia may have disease-modifying effects on PD. <b>Methods:</b> Herein, we investigated whethe...

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Main Authors: Ha Nyeoung Choi, Seon-Hee Kim, Min Gi Jo, Bina Lee, Young Jin Kim, So Eun Lee, Jeong Hyun Lee, Hye Min Seong, Seong Jae Kim, Sang Won Park, Hye Jung Kim, Heeyoung Kang, Chan Hyun Lee, Min Young Lee, Seung Pil Yun, Minkyeong Kim
Format: Article
Language:English
Published: MDPI AG 2025-03-01
Series:Biomedicines
Subjects:
Parkinson’s disease (PD)
hypoxia
astrocyte
neuronal death
pre-formed fibril
Online Access:https://www.mdpi.com/2227-9059/13/3/604
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