Antibacterial Activity of Selected Essential Oil Components and Their Derivatives: A Review

Essential oils (EOs) are gaining ground and have been intensively studied due to their widespread use in the pharmaceutical, food, and cosmetics industries. The essential components of EOs have been recognized for diverse therapeutic activities and have gained significant attention for their potenti...

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Main Authors: Vuyolwethu Khwaza, Blessing A. Aderibigbe
Format: Article
Language:English
Published: MDPI AG 2025-01-01
Series:Antibiotics
Subjects:
Online Access:https://www.mdpi.com/2079-6382/14/1/68
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author Vuyolwethu Khwaza
Blessing A. Aderibigbe
author_facet Vuyolwethu Khwaza
Blessing A. Aderibigbe
author_sort Vuyolwethu Khwaza
collection DOAJ
description Essential oils (EOs) are gaining ground and have been intensively studied due to their widespread use in the pharmaceutical, food, and cosmetics industries. The essential components of EOs have been recognized for diverse therapeutic activities and have gained significant attention for their potential antibacterial activities. Despite the popularity of EOs and potent biological properties, their bioactive components and their derivatives are still not comprehensively characterized. This review explores the antibacterial efficacy of selected EO components and their derivatives, focusing on monoterpenes chosen (i.e., carvacrol, menthol, and thymol) and phenylpropanoids (i.e., cinnamaldehyde and eugenol). Furthermore, this review highlights recent advancements in developing derivatives of these EO components, which have shown improved antibacterial activity with reduced toxicity. By summarizing recent studies, this review reveals the potential of these natural compounds and their derivatives as promising candidates for pharmaceuticals, food preservation, and as alternatives to synthetic antibiotics in combating bacterial resistance.
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institution Kabale University
issn 2079-6382
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publisher MDPI AG
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series Antibiotics
spelling doaj-art-7090a1e821114881b874e5ff21a8734c2025-01-24T13:18:50ZengMDPI AGAntibiotics2079-63822025-01-011416810.3390/antibiotics14010068Antibacterial Activity of Selected Essential Oil Components and Their Derivatives: A ReviewVuyolwethu Khwaza0Blessing A. Aderibigbe1Department of Chemistry, Faculty of Science and Agriculture, University of Fort Hare, Alice Campus, Alice 5700, South AfricaDepartment of Chemistry, Faculty of Science and Agriculture, University of Fort Hare, Alice Campus, Alice 5700, South AfricaEssential oils (EOs) are gaining ground and have been intensively studied due to their widespread use in the pharmaceutical, food, and cosmetics industries. The essential components of EOs have been recognized for diverse therapeutic activities and have gained significant attention for their potential antibacterial activities. Despite the popularity of EOs and potent biological properties, their bioactive components and their derivatives are still not comprehensively characterized. This review explores the antibacterial efficacy of selected EO components and their derivatives, focusing on monoterpenes chosen (i.e., carvacrol, menthol, and thymol) and phenylpropanoids (i.e., cinnamaldehyde and eugenol). Furthermore, this review highlights recent advancements in developing derivatives of these EO components, which have shown improved antibacterial activity with reduced toxicity. By summarizing recent studies, this review reveals the potential of these natural compounds and their derivatives as promising candidates for pharmaceuticals, food preservation, and as alternatives to synthetic antibiotics in combating bacterial resistance.https://www.mdpi.com/2079-6382/14/1/68antibacterial activityessential oilsnatural productsmonoterpenesphenylpropanoidsderivatives/analogs
spellingShingle Vuyolwethu Khwaza
Blessing A. Aderibigbe
Antibacterial Activity of Selected Essential Oil Components and Their Derivatives: A Review
Antibiotics
antibacterial activity
essential oils
natural products
monoterpenes
phenylpropanoids
derivatives/analogs
title Antibacterial Activity of Selected Essential Oil Components and Their Derivatives: A Review
title_full Antibacterial Activity of Selected Essential Oil Components and Their Derivatives: A Review
title_fullStr Antibacterial Activity of Selected Essential Oil Components and Their Derivatives: A Review
title_full_unstemmed Antibacterial Activity of Selected Essential Oil Components and Their Derivatives: A Review
title_short Antibacterial Activity of Selected Essential Oil Components and Their Derivatives: A Review
title_sort antibacterial activity of selected essential oil components and their derivatives a review
topic antibacterial activity
essential oils
natural products
monoterpenes
phenylpropanoids
derivatives/analogs
url https://www.mdpi.com/2079-6382/14/1/68
work_keys_str_mv AT vuyolwethukhwaza antibacterialactivityofselectedessentialoilcomponentsandtheirderivativesareview
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