Differential Fasting Plasma Glucose and Ketone Body Levels in GHRKO versus 3xTg-AD Mice: A Potential Contributor to Aging-Related Cognitive Status?
Cognitive function declines with age and appears to correlate with decreased cerebral metabolic rate (CMR). Caloric restriction, an antiaging manipulation that extends life-span and can preserve cognitive function, is associated with decreased glucose uptake, decreased lactate levels, and increased...
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Main Authors: | Chelsea M. Griffith, Lauren N. Macklin, Andrzej Bartke, Peter R. Patrylo |
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Format: | Article |
Language: | English |
Published: |
Wiley
2017-01-01
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Series: | International Journal of Endocrinology |
Online Access: | http://dx.doi.org/10.1155/2017/9684061 |
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