Canadian Clinical Practice Guidelines for Invasive Candidiasis in Adults

Candidemia and invasive candidiasis (C/IC) are life-threatening opportunistic infections that add excess morbidity, mortality and cost to the management of patients with a range of potentially curable underlying conditions. The Association of Medical Microbiology and Infectious Disease Canada develo...

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Main Authors: Eric J Bow, Gerald Evans, Jeff Fuller, Michel Laverdière, Coleman Rotstein, Robert Rennie, Stephen D Shafran, Don Sheppard, Sylvie Carle, Peter Phillips, Donald C Vinh
Format: Article
Language:English
Published: Wiley 2010-01-01
Series:Canadian Journal of Infectious Diseases and Medical Microbiology
Online Access:http://dx.doi.org/10.1155/2010/357076
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author Eric J Bow
Gerald Evans
Jeff Fuller
Michel Laverdière
Coleman Rotstein
Robert Rennie
Stephen D Shafran
Don Sheppard
Sylvie Carle
Peter Phillips
Donald C Vinh
author_facet Eric J Bow
Gerald Evans
Jeff Fuller
Michel Laverdière
Coleman Rotstein
Robert Rennie
Stephen D Shafran
Don Sheppard
Sylvie Carle
Peter Phillips
Donald C Vinh
author_sort Eric J Bow
collection DOAJ
description Candidemia and invasive candidiasis (C/IC) are life-threatening opportunistic infections that add excess morbidity, mortality and cost to the management of patients with a range of potentially curable underlying conditions. The Association of Medical Microbiology and Infectious Disease Canada developed evidence-based guidelines for the approach to the diagnosis and management of these infections in the ever-increasing population of at-risk adult patients in the health care system. Over the past few years, a new and broader understanding of the epidemiology and pathogenesis of C/IC has emerged and has been coupled with the availability of new antifungal agents and defined strategies for targeting groups at risk including, but not limited to, acute leukemia patients, hematopoietic stem cell transplants and solid organ transplants, and critical care unit patients. Accordingly, these guidelines have focused on patients at risk for C/IC, and on approaches of prevention, early therapy for suspected but unproven infection, and targeted therapy for probable and proven infection.
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spelling doaj-art-7083eadf90374231808cdd1a2712c48b2025-02-03T05:45:44ZengWileyCanadian Journal of Infectious Diseases and Medical Microbiology1712-95322010-01-01214e122e15010.1155/2010/357076Canadian Clinical Practice Guidelines for Invasive Candidiasis in AdultsEric J Bow0Gerald Evans1Jeff Fuller2Michel Laverdière3Coleman Rotstein4Robert Rennie5Stephen D Shafran6Don Sheppard7Sylvie Carle8Peter Phillips9Donald C Vinh10Department of Medical Microbiology and Infectious Diseases, University of Manitoba; Clinical and Academic Services, and Infection Control Services, Cancer Care Manitoba; Oncology Program, Winnipeg Regional Health Authority, Winnipeg, Manitoba, CanadaDivision of Infectious Diseases, Department of Medicine, Queen’s University, Kingston General Hospital, Kingston, Ontario, CanadaDepartment of Laboratory Medicine and Pathology, University of Alberta, University of Alberta Hospital, Edmonton, Alberta, CanadaDepartment of Microbiology-Infectious Diseases, University of Montreal, Laboratory Program, Hôpital Maisonneuve-Rosemont, Montreal, Quebec, CanadaDivision of Infectious Disease, Department of Medicine, University of Toronto and Transplant Infectious Diseases, Oncologic Infectious Diseases, University Health Network, Toronto, Ontario, CanadaDepartment of Laboratory Medicine and Pathology, University of Alberta, University of Alberta Hospital, Edmonton, Alberta, CanadaDivision of Infectious Diseases, Department of Medicine, University of Alberta, Capital Health Authority, Edmonton, Alberta, CanadaDepartments of Medicine, and Microbiology and Immunology, McGill University, Montreal, Quebec, CanadaDepartment of Pharmacy, University of Montreal, McGill University Health Centre, Montreal, Quebec, CanadaDivision of Infectious Diseases, Department of Medicine, University of British Columbia, St Paul’s Hospital, Vancouver, British Columbia, CanadaDivision of Infectious Diseases, Department of Medicine, Department of Medical Microbiology, McGill University, Montreal, Quebec and Laboratory of Clinical Infectious Diseases, CanadaCandidemia and invasive candidiasis (C/IC) are life-threatening opportunistic infections that add excess morbidity, mortality and cost to the management of patients with a range of potentially curable underlying conditions. The Association of Medical Microbiology and Infectious Disease Canada developed evidence-based guidelines for the approach to the diagnosis and management of these infections in the ever-increasing population of at-risk adult patients in the health care system. Over the past few years, a new and broader understanding of the epidemiology and pathogenesis of C/IC has emerged and has been coupled with the availability of new antifungal agents and defined strategies for targeting groups at risk including, but not limited to, acute leukemia patients, hematopoietic stem cell transplants and solid organ transplants, and critical care unit patients. Accordingly, these guidelines have focused on patients at risk for C/IC, and on approaches of prevention, early therapy for suspected but unproven infection, and targeted therapy for probable and proven infection.http://dx.doi.org/10.1155/2010/357076
spellingShingle Eric J Bow
Gerald Evans
Jeff Fuller
Michel Laverdière
Coleman Rotstein
Robert Rennie
Stephen D Shafran
Don Sheppard
Sylvie Carle
Peter Phillips
Donald C Vinh
Canadian Clinical Practice Guidelines for Invasive Candidiasis in Adults
Canadian Journal of Infectious Diseases and Medical Microbiology
title Canadian Clinical Practice Guidelines for Invasive Candidiasis in Adults
title_full Canadian Clinical Practice Guidelines for Invasive Candidiasis in Adults
title_fullStr Canadian Clinical Practice Guidelines for Invasive Candidiasis in Adults
title_full_unstemmed Canadian Clinical Practice Guidelines for Invasive Candidiasis in Adults
title_short Canadian Clinical Practice Guidelines for Invasive Candidiasis in Adults
title_sort canadian clinical practice guidelines for invasive candidiasis in adults
url http://dx.doi.org/10.1155/2010/357076
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