Atrial Fibrillation after Inhalational Lung Injury: A Troubling Complication of a Rare Problem

Atrial fibrillation (AF) has been associated with lung diseases like pneumonia and chronic obstructive pulmonary disease but has only infrequently been associated with inhalational lung injury. We report two cases of resistant AF, which developed in young healthy manual laborers shortly after inhala...

Full description

Saved in:
Bibliographic Details
Main Authors: Ragesh Panikkath, Kenneth Nugent, Alejandro Perez-Verdia
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:Case Reports in Medicine
Online Access:http://dx.doi.org/10.1155/2012/302057
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1832566543721955328
author Ragesh Panikkath
Kenneth Nugent
Alejandro Perez-Verdia
author_facet Ragesh Panikkath
Kenneth Nugent
Alejandro Perez-Verdia
author_sort Ragesh Panikkath
collection DOAJ
description Atrial fibrillation (AF) has been associated with lung diseases like pneumonia and chronic obstructive pulmonary disease but has only infrequently been associated with inhalational lung injury. We report two cases of resistant AF, which developed in young healthy manual laborers shortly after inhalational lung injury due to massive quantity of pesticides and anhydrous ammonia, respectively. They had no evidence of valvular or structural heart disease and did not have any previous medical problems. The AF was resistant to antiarrhythmic drugs and required pulmonary vein isolation in first patient and possibly the second patient who is currently being evaluated for this procedure. These arrhythmias may reflect direct myocardial injury during and after exposure. Alternatively, multiple mechanisms can cause atrial fibrillation in lung diseases, including hypoxemia, acidemia, inflammatory mediators, and structural changes in the atria and ventricle, and these could lead to AF in inhalational lung injury cases. AF needs to be excluded when patients present with palpitations after inhalational lung injury, especially since, if unrecognized, AF may lead to complications, like thromboembolic phenomenon and tachycardiomyopathy.
format Article
id doaj-art-70726a8bd4bb40beaf544ca87b374358
institution Kabale University
issn 1687-9627
1687-9635
language English
publishDate 2012-01-01
publisher Wiley
record_format Article
series Case Reports in Medicine
spelling doaj-art-70726a8bd4bb40beaf544ca87b3743582025-02-03T01:03:44ZengWileyCase Reports in Medicine1687-96271687-96352012-01-01201210.1155/2012/302057302057Atrial Fibrillation after Inhalational Lung Injury: A Troubling Complication of a Rare ProblemRagesh Panikkath0Kenneth Nugent1Alejandro Perez-Verdia2Department of Internal Medicine, Texas Tech University Health Sciences Center, Lubbock, TX 79430, USADepartment of Internal Medicine, Texas Tech University Health Sciences Center, Lubbock, TX 79430, USADepartment of Internal Medicine, Texas Tech University Health Sciences Center, Lubbock, TX 79430, USAAtrial fibrillation (AF) has been associated with lung diseases like pneumonia and chronic obstructive pulmonary disease but has only infrequently been associated with inhalational lung injury. We report two cases of resistant AF, which developed in young healthy manual laborers shortly after inhalational lung injury due to massive quantity of pesticides and anhydrous ammonia, respectively. They had no evidence of valvular or structural heart disease and did not have any previous medical problems. The AF was resistant to antiarrhythmic drugs and required pulmonary vein isolation in first patient and possibly the second patient who is currently being evaluated for this procedure. These arrhythmias may reflect direct myocardial injury during and after exposure. Alternatively, multiple mechanisms can cause atrial fibrillation in lung diseases, including hypoxemia, acidemia, inflammatory mediators, and structural changes in the atria and ventricle, and these could lead to AF in inhalational lung injury cases. AF needs to be excluded when patients present with palpitations after inhalational lung injury, especially since, if unrecognized, AF may lead to complications, like thromboembolic phenomenon and tachycardiomyopathy.http://dx.doi.org/10.1155/2012/302057
spellingShingle Ragesh Panikkath
Kenneth Nugent
Alejandro Perez-Verdia
Atrial Fibrillation after Inhalational Lung Injury: A Troubling Complication of a Rare Problem
Case Reports in Medicine
title Atrial Fibrillation after Inhalational Lung Injury: A Troubling Complication of a Rare Problem
title_full Atrial Fibrillation after Inhalational Lung Injury: A Troubling Complication of a Rare Problem
title_fullStr Atrial Fibrillation after Inhalational Lung Injury: A Troubling Complication of a Rare Problem
title_full_unstemmed Atrial Fibrillation after Inhalational Lung Injury: A Troubling Complication of a Rare Problem
title_short Atrial Fibrillation after Inhalational Lung Injury: A Troubling Complication of a Rare Problem
title_sort atrial fibrillation after inhalational lung injury a troubling complication of a rare problem
url http://dx.doi.org/10.1155/2012/302057
work_keys_str_mv AT rageshpanikkath atrialfibrillationafterinhalationallunginjuryatroublingcomplicationofarareproblem
AT kennethnugent atrialfibrillationafterinhalationallunginjuryatroublingcomplicationofarareproblem
AT alejandroperezverdia atrialfibrillationafterinhalationallunginjuryatroublingcomplicationofarareproblem