Improving sensitivity in the deep regions of a volume conductor using electrical focused impedance methods

Bioimpedance measurements are becoming important in probing the human body for diagnosis and monitoring. An age old 4-electrode technique called tetrapolar impedance measurement (TPIM), giving transfer impedance, cannot localize a specific zone besides having large zones of negative sensitivity. A n...

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Main Authors: Mobarak Mahjabin, Rabbani K Siddique-e
Format: Article
Language:English
Published: Sciendo 2024-09-01
Series:Journal of Electrical Bioimpedance
Subjects:
Online Access:https://doi.org/10.2478/joeb-2024-0012
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author Mobarak Mahjabin
Rabbani K Siddique-e
author_facet Mobarak Mahjabin
Rabbani K Siddique-e
author_sort Mobarak Mahjabin
collection DOAJ
description Bioimpedance measurements are becoming important in probing the human body for diagnosis and monitoring. An age old 4-electrode technique called tetrapolar impedance measurement (TPIM), giving transfer impedance, cannot localize a specific zone besides having large zones of negative sensitivity. A new technique named the focused impedance method (FIM) from Dhaka University (DU), Bangladesh used the algebraic average of two concentric and orthogonal TPIMs, localizing a zone of interest and having reduced magnitudes of negative sensitivity. Earlier, this was implemented with electrodes applied from one side of the human body giving information to shallow depths only. To get information from deeper regions, specifically, of the thorax, the same DU group placed two electrodes of a 4-electrode version of FIM at the front and two at the back in a horizontal plane of the thorax, using physics-based visualization. This was followed by a few quantitative studies using point sensitivity, which supported the concept. However, more quantitative studies still need to be performed, particularly using objects of finite sizes, in order to establish the technique on a stronger footing. The present study was taken up with this objective. A simplified approach was used in which the volume conductor was a rectangular non-conducting container filled with saline of uniform conductivity with an embedded spherical object – first an insulator and then a conductor. Electrodes were placed at specific chosen positions following the above visualization. Percentage change in transfer impedance with the object placed at different internal positions, compared to that without the object was obtained first using COMSOL simulation and then through experimental measurements. These were performed for both TPIM and FIM. The new configuration of 4-electrode FIM gave good depth sensitivity supporting the effectiveness of the new placement of electrodes.
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spelling doaj-art-705ca501d05e441dab39bf2e89a13cac2025-01-20T11:09:56ZengSciendoJournal of Electrical Bioimpedance1891-54692024-09-0115110711510.2478/joeb-2024-0012Improving sensitivity in the deep regions of a volume conductor using electrical focused impedance methodsMobarak Mahjabin0Rabbani K Siddique-e11Southeast University, Dhaka, Bangladesh2Department of Biomedical Physics and Technology, University of Dhaka, Dhaka, BangladeshBioimpedance measurements are becoming important in probing the human body for diagnosis and monitoring. An age old 4-electrode technique called tetrapolar impedance measurement (TPIM), giving transfer impedance, cannot localize a specific zone besides having large zones of negative sensitivity. A new technique named the focused impedance method (FIM) from Dhaka University (DU), Bangladesh used the algebraic average of two concentric and orthogonal TPIMs, localizing a zone of interest and having reduced magnitudes of negative sensitivity. Earlier, this was implemented with electrodes applied from one side of the human body giving information to shallow depths only. To get information from deeper regions, specifically, of the thorax, the same DU group placed two electrodes of a 4-electrode version of FIM at the front and two at the back in a horizontal plane of the thorax, using physics-based visualization. This was followed by a few quantitative studies using point sensitivity, which supported the concept. However, more quantitative studies still need to be performed, particularly using objects of finite sizes, in order to establish the technique on a stronger footing. The present study was taken up with this objective. A simplified approach was used in which the volume conductor was a rectangular non-conducting container filled with saline of uniform conductivity with an embedded spherical object – first an insulator and then a conductor. Electrodes were placed at specific chosen positions following the above visualization. Percentage change in transfer impedance with the object placed at different internal positions, compared to that without the object was obtained first using COMSOL simulation and then through experimental measurements. These were performed for both TPIM and FIM. The new configuration of 4-electrode FIM gave good depth sensitivity supporting the effectiveness of the new placement of electrodes.https://doi.org/10.2478/joeb-2024-0012electrical impedancetetrapolar impedance method (tpim)focused impedance method (fim)transfer impedancedeep probing of thorax
spellingShingle Mobarak Mahjabin
Rabbani K Siddique-e
Improving sensitivity in the deep regions of a volume conductor using electrical focused impedance methods
Journal of Electrical Bioimpedance
electrical impedance
tetrapolar impedance method (tpim)
focused impedance method (fim)
transfer impedance
deep probing of thorax
title Improving sensitivity in the deep regions of a volume conductor using electrical focused impedance methods
title_full Improving sensitivity in the deep regions of a volume conductor using electrical focused impedance methods
title_fullStr Improving sensitivity in the deep regions of a volume conductor using electrical focused impedance methods
title_full_unstemmed Improving sensitivity in the deep regions of a volume conductor using electrical focused impedance methods
title_short Improving sensitivity in the deep regions of a volume conductor using electrical focused impedance methods
title_sort improving sensitivity in the deep regions of a volume conductor using electrical focused impedance methods
topic electrical impedance
tetrapolar impedance method (tpim)
focused impedance method (fim)
transfer impedance
deep probing of thorax
url https://doi.org/10.2478/joeb-2024-0012
work_keys_str_mv AT mobarakmahjabin improvingsensitivityinthedeepregionsofavolumeconductorusingelectricalfocusedimpedancemethods
AT rabbaniksiddiquee improvingsensitivityinthedeepregionsofavolumeconductorusingelectricalfocusedimpedancemethods