Inhibitory effects of high extracellular l-glutamate concentrations on skeletal myogenesis

Abstract l-glutamate (Glu) is accumulated abundantly in skeletal muscle cells and plays a central role in energy production, amino acid metabolism, and protein synthesis. If intracellular Glu leaks due to plasma membrane fragility or injury, it may adversely affect the surrounding myocytes. In the p...

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Bibliographic Details
Main Authors: Himiko Ban, Koji Nobe, Soushi Kobayashi
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Scientific Reports
Subjects:
Online Access:https://doi.org/10.1038/s41598-025-01840-3
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