Discoidin domain receptor 2 is an important modulator of BMP signaling during heterotopic bone formation

Discoidin domain receptor 2 is an important modulator of BMP signaling during heterotopic bone formation

Abstract Bone morphogenetic proteins are essential for bone regeneration/fracture healing but can also induce heterotopic ossification (HO). Understanding accessory factors modulating BMP signaling would provide both a means of enhancing BMP-dependent regeneration while preventing HO. This study foc...

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Bibliographic Details
Main Authors: Fashuai Wu, Chunxi Ge, Haichun Pan, Yuanyuan Han, Yuji Mishina, Vesa Kaartinen, Renny T. Franceschi
Format: Article
Language:English
Published: Nature Publishing Group 2025-01-01
Series:Bone Research
Online Access:https://doi.org/10.1038/s41413-024-00391-z
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