Rapid Multiorgan Dissemination of Low-Grade Myxofibrosarcoma: A Case Report

Myxofibrosarcoma is one of the most common sarcomas in the extremities of elderly people. It is characterized by a high frequency of local recurrence due to an infiltrative growth property. In contrast, the overall risk of distant metastases is generally low. This makes the prognosis for the patient...

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Main Authors: Yasutaka Murahashi, Mitsunori Kaya, Tamotsu Soma, Mikito Sasaki, Satoshi Nagoya, Takuro Wada, Toshihiko Yamashita
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:Case Reports in Medicine
Online Access:http://dx.doi.org/10.1155/2012/310805
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author Yasutaka Murahashi
Mitsunori Kaya
Tamotsu Soma
Mikito Sasaki
Satoshi Nagoya
Takuro Wada
Toshihiko Yamashita
author_facet Yasutaka Murahashi
Mitsunori Kaya
Tamotsu Soma
Mikito Sasaki
Satoshi Nagoya
Takuro Wada
Toshihiko Yamashita
author_sort Yasutaka Murahashi
collection DOAJ
description Myxofibrosarcoma is one of the most common sarcomas in the extremities of elderly people. It is characterized by a high frequency of local recurrence due to an infiltrative growth property. In contrast, the overall risk of distant metastases is generally low. This makes the prognosis for the patients with myxofibrosarcoma definitely good. In this paper, we will report the case of a 79-year-old female with very aggressive metastatic low-grade myxofibrosarcoma. The disease progression was really unexpected and misled every possible medical interpretation, leading to rapid worsening of the patient's clinical conditions and no chance for therapy. The tumor developed diffuse infiltration in lung, spine, skeletal bone, abdomen, paravertebral muscles, and liver. The patient died 8 months after the diagnosis of remote metastases due to rapid tumor progression.
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spelling doaj-art-700c815a07b64fdfa274d1d1064fdeb92025-02-03T05:53:19ZengWileyCase Reports in Medicine1687-96271687-96352012-01-01201210.1155/2012/310805310805Rapid Multiorgan Dissemination of Low-Grade Myxofibrosarcoma: A Case ReportYasutaka Murahashi0Mitsunori Kaya1Tamotsu Soma2Mikito Sasaki3Satoshi Nagoya4Takuro Wada5Toshihiko Yamashita6Department of Orthopaedic Surgery, Sapporo Medical University School of Medicine, S-1, W-16, Chuo-ku, Sapporo, Hokkaido 060-8543, JapanDepartment of Orthopaedic Surgery, Sapporo Medical University School of Medicine, S-1, W-16, Chuo-ku, Sapporo, Hokkaido 060-8543, JapanDepartment of Orthopaedic Surgery, Sapporo Medical University School of Medicine, S-1, W-16, Chuo-ku, Sapporo, Hokkaido 060-8543, JapanDepartment of Orthopaedic Surgery, Sapporo Medical University School of Medicine, S-1, W-16, Chuo-ku, Sapporo, Hokkaido 060-8543, JapanDepartment of Orthopaedic Surgery, Sapporo Medical University School of Medicine, S-1, W-16, Chuo-ku, Sapporo, Hokkaido 060-8543, JapanDepartment of Orthopaedic Surgery, Sapporo Medical University School of Medicine, S-1, W-16, Chuo-ku, Sapporo, Hokkaido 060-8543, JapanDepartment of Orthopaedic Surgery, Sapporo Medical University School of Medicine, S-1, W-16, Chuo-ku, Sapporo, Hokkaido 060-8543, JapanMyxofibrosarcoma is one of the most common sarcomas in the extremities of elderly people. It is characterized by a high frequency of local recurrence due to an infiltrative growth property. In contrast, the overall risk of distant metastases is generally low. This makes the prognosis for the patients with myxofibrosarcoma definitely good. In this paper, we will report the case of a 79-year-old female with very aggressive metastatic low-grade myxofibrosarcoma. The disease progression was really unexpected and misled every possible medical interpretation, leading to rapid worsening of the patient's clinical conditions and no chance for therapy. The tumor developed diffuse infiltration in lung, spine, skeletal bone, abdomen, paravertebral muscles, and liver. The patient died 8 months after the diagnosis of remote metastases due to rapid tumor progression.http://dx.doi.org/10.1155/2012/310805
spellingShingle Yasutaka Murahashi
Mitsunori Kaya
Tamotsu Soma
Mikito Sasaki
Satoshi Nagoya
Takuro Wada
Toshihiko Yamashita
Rapid Multiorgan Dissemination of Low-Grade Myxofibrosarcoma: A Case Report
Case Reports in Medicine
title Rapid Multiorgan Dissemination of Low-Grade Myxofibrosarcoma: A Case Report
title_full Rapid Multiorgan Dissemination of Low-Grade Myxofibrosarcoma: A Case Report
title_fullStr Rapid Multiorgan Dissemination of Low-Grade Myxofibrosarcoma: A Case Report
title_full_unstemmed Rapid Multiorgan Dissemination of Low-Grade Myxofibrosarcoma: A Case Report
title_short Rapid Multiorgan Dissemination of Low-Grade Myxofibrosarcoma: A Case Report
title_sort rapid multiorgan dissemination of low grade myxofibrosarcoma a case report
url http://dx.doi.org/10.1155/2012/310805
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