In situ Apoptotic and Proliferation Index in Laryngeal Squamous Cell Carcinomas
The rate of cellular growth is mainly influenced by the balance between cell proliferation and cellular decay. Since to our knowledge, no study so far has analysed the rate of proliferation and apoptosis in the normal laryngeal mucosa and in invasive laryngeal carcinomas, we performed a morphologica...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
1998-01-01
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| Series: | Analytical Cellular Pathology |
| Online Access: | http://dx.doi.org/10.1155/1998/913984 |
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| _version_ | 1832563089139040256 |
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| author | Hjalmar G. Hagedorn Jutta Tübel Irmgard Wiest Andreas G. Nerlich |
| author_facet | Hjalmar G. Hagedorn Jutta Tübel Irmgard Wiest Andreas G. Nerlich |
| author_sort | Hjalmar G. Hagedorn |
| collection | DOAJ |
| description | The rate of cellular growth is mainly influenced by the balance between cell proliferation and cellular decay. Since to our knowledge, no study so far has analysed the rate of proliferation and apoptosis in the normal laryngeal mucosa and in invasive laryngeal carcinomas, we performed a morphological analysis on both parameters in biopsies from 30 patients with laryngeal carcinoma. We applied the TUNEL end labelling technique for the investigation of apoptosis and immunohistochemistry (Ki‐67 antigen) for the determination of the cell proliferation. |
| format | Article |
| id | doaj-art-6fe3d6a8eca649a6b366b788e39836a6 |
| institution | Kabale University |
| issn | 0921-8912 1878-3651 |
| language | English |
| publishDate | 1998-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Analytical Cellular Pathology |
| spelling | doaj-art-6fe3d6a8eca649a6b366b788e39836a62025-02-03T01:21:02ZengWileyAnalytical Cellular Pathology0921-89121878-36511998-01-0116317718410.1155/1998/913984In situ Apoptotic and Proliferation Index in Laryngeal Squamous Cell CarcinomasHjalmar G. Hagedorn0Jutta Tübel1Irmgard Wiest2Andreas G. Nerlich3Department of ENT‐Diseases and Head and Neck Surgery, University of Munich, Klinikum Großhadern, Marchioninistr. 15, D‐81377 München, GermanyInstitute for Pathology, University of Munich, Thalkirchnerstr. 36, D‐80337 München, GermanyInstitute for Pathology, University of Munich, Thalkirchnerstr. 36, D‐80337 München, GermanyInstitute for Pathology, University of Munich, Thalkirchnerstr. 36, D‐80337 München, GermanyThe rate of cellular growth is mainly influenced by the balance between cell proliferation and cellular decay. Since to our knowledge, no study so far has analysed the rate of proliferation and apoptosis in the normal laryngeal mucosa and in invasive laryngeal carcinomas, we performed a morphological analysis on both parameters in biopsies from 30 patients with laryngeal carcinoma. We applied the TUNEL end labelling technique for the investigation of apoptosis and immunohistochemistry (Ki‐67 antigen) for the determination of the cell proliferation.http://dx.doi.org/10.1155/1998/913984 |
| spellingShingle | Hjalmar G. Hagedorn Jutta Tübel Irmgard Wiest Andreas G. Nerlich In situ Apoptotic and Proliferation Index in Laryngeal Squamous Cell Carcinomas Analytical Cellular Pathology |
| title | In situ Apoptotic and Proliferation Index in Laryngeal Squamous Cell Carcinomas |
| title_full | In situ Apoptotic and Proliferation Index in Laryngeal Squamous Cell Carcinomas |
| title_fullStr | In situ Apoptotic and Proliferation Index in Laryngeal Squamous Cell Carcinomas |
| title_full_unstemmed | In situ Apoptotic and Proliferation Index in Laryngeal Squamous Cell Carcinomas |
| title_short | In situ Apoptotic and Proliferation Index in Laryngeal Squamous Cell Carcinomas |
| title_sort | in situ apoptotic and proliferation index in laryngeal squamous cell carcinomas |
| url | http://dx.doi.org/10.1155/1998/913984 |
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