Statin use during intensive care unit stay is associated with improved clinical outcomes in critically ill patients with sepsis: a cohort study

Statin use during intensive care unit stay is associated with improved clinical outcomes in critically ill patients with sepsis: a cohort study

BackgroundDespite early goal-directed therapy, sepsis mortality remains high. Statins exhibit pleiotropic effects, including anti-inflammatory and antimicrobial properties, which may be beneficial during sepsis.ObjectiveTo determine whether statins could improve the clinical outcomes in patients wit...

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Bibliographic Details
Main Authors: Caifeng Li, Ke Zhao, Qian Ren, Lin Chen, Ying Zhang, Guolin Wang, Keliang Xie
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Immunology
Subjects:
critical illness
mortality
intensive care unit
statin
sepsis
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1537172/full
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