False-Positive 18F-FDG PET/CT Uptake in Unilateral Lactation
A 31-year-old woman (7 months postpartum and lactating) with multiple sclerotic bone lesions was referred for an 18F-FDG PET/CT scan for characterization. The scan demonstrated unilateral diffuse intense FDG uptake corresponding to dense soft tissue in the right breast, likely related to secretory h...
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| Format: | Article |
| Language: | English |
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Wiley
2020-01-01
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| Series: | Case Reports in Radiology |
| Online Access: | http://dx.doi.org/10.1155/2020/8850052 |
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| author | Joshua Wei Liang Yip Han Loh Chuong Bui Veronica Chi Ken Wong Robert Mansberg |
| author_facet | Joshua Wei Liang Yip Han Loh Chuong Bui Veronica Chi Ken Wong Robert Mansberg |
| author_sort | Joshua Wei Liang Yip |
| collection | DOAJ |
| description | A 31-year-old woman (7 months postpartum and lactating) with multiple sclerotic bone lesions was referred for an 18F-FDG PET/CT scan for characterization. The scan demonstrated unilateral diffuse intense FDG uptake corresponding to dense soft tissue in the right breast, likely related to secretory hyperplasia. On further questioning, it was made apparent that she had only been breastfeeding from the right breast. While the left breast also demonstrated dense soft tissue to a lesser degree, no significant FDG uptake was seen. The sclerotic bone lesions were not FDG avid, likely due to a separate non-FDG avid benign condition or bony metastases from a non-FDG avid primary malignancy. This was reinforced by the fact that subsequent investigations including serial bilateral breast ultrasound and percutaneous biopsy demonstrated no definite evidence of malignancy in the bilateral breasts. The histopathology findings of an open surgical biopsy of sclerotic lesions in the left posterior ilium were also nonspecific, favouring bone dysplasia with no evidence of malignancy. |
| format | Article |
| id | doaj-art-6fbcc80e3c3042a9b4ce6e030f9ee2c0 |
| institution | Kabale University |
| issn | 2090-6862 2090-6870 |
| language | English |
| publishDate | 2020-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Radiology |
| spelling | doaj-art-6fbcc80e3c3042a9b4ce6e030f9ee2c02025-02-03T01:28:08ZengWileyCase Reports in Radiology2090-68622090-68702020-01-01202010.1155/2020/88500528850052False-Positive 18F-FDG PET/CT Uptake in Unilateral LactationJoshua Wei Liang Yip0Han Loh1Chuong Bui2Veronica Chi Ken Wong3Robert Mansberg4Department of Nuclear Medicine and PET, Nepean Hospital, Derby St, Kingswood NSW 2747, AustraliaDepartment of Nuclear Medicine and PET, Nepean Hospital, Derby St, Kingswood NSW 2747, AustraliaDepartment of Nuclear Medicine and PET, Nepean Hospital, Derby St, Kingswood NSW 2747, AustraliaDepartment of Nuclear Medicine and PET, Nepean Hospital, Derby St, Kingswood NSW 2747, AustraliaDepartment of Nuclear Medicine and PET, Nepean Hospital, Derby St, Kingswood NSW 2747, AustraliaA 31-year-old woman (7 months postpartum and lactating) with multiple sclerotic bone lesions was referred for an 18F-FDG PET/CT scan for characterization. The scan demonstrated unilateral diffuse intense FDG uptake corresponding to dense soft tissue in the right breast, likely related to secretory hyperplasia. On further questioning, it was made apparent that she had only been breastfeeding from the right breast. While the left breast also demonstrated dense soft tissue to a lesser degree, no significant FDG uptake was seen. The sclerotic bone lesions were not FDG avid, likely due to a separate non-FDG avid benign condition or bony metastases from a non-FDG avid primary malignancy. This was reinforced by the fact that subsequent investigations including serial bilateral breast ultrasound and percutaneous biopsy demonstrated no definite evidence of malignancy in the bilateral breasts. The histopathology findings of an open surgical biopsy of sclerotic lesions in the left posterior ilium were also nonspecific, favouring bone dysplasia with no evidence of malignancy.http://dx.doi.org/10.1155/2020/8850052 |
| spellingShingle | Joshua Wei Liang Yip Han Loh Chuong Bui Veronica Chi Ken Wong Robert Mansberg False-Positive 18F-FDG PET/CT Uptake in Unilateral Lactation Case Reports in Radiology |
| title | False-Positive 18F-FDG PET/CT Uptake in Unilateral Lactation |
| title_full | False-Positive 18F-FDG PET/CT Uptake in Unilateral Lactation |
| title_fullStr | False-Positive 18F-FDG PET/CT Uptake in Unilateral Lactation |
| title_full_unstemmed | False-Positive 18F-FDG PET/CT Uptake in Unilateral Lactation |
| title_short | False-Positive 18F-FDG PET/CT Uptake in Unilateral Lactation |
| title_sort | false positive 18f fdg pet ct uptake in unilateral lactation |
| url | http://dx.doi.org/10.1155/2020/8850052 |
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