Synthesis and Anti-Inflammatory Activity of New Alkyl-Substituted Phthalimide 1H-1,2,3-Triazole Derivatives

Synthesis and Anti-Inflammatory Activity of New Alkyl-Substituted Phthalimide 1H-1,2,3-Triazole Derivatives

Four new 1,2,3-triazole phthalimide derivatives with a potent anti-inflammatory activity have been synthesized in the good yields by the 1,3-dipolar cycloaddition reaction from N-(azido-alkyl)phthalimides and terminal alkynes. The anti-inflammatory activity was determined by injecting carrageenan th...

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Bibliographic Details
Main Authors:	Shalom Pôrto de Oliveira Assis, Moara Targino da Silva, Ronaldo Nascimento de Oliveira, Vera Lúcia de Menezes Lima
Format:	Article
Language:	English
Published:	Wiley 2012-01-01
Series:	The Scientific World Journal
Online Access:	http://dx.doi.org/10.1100/2012/925925
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