Unraveling the heterogeneity of WHO grade 4 gliomas: insights from clinical, imaging, and molecular characterization

Unraveling the heterogeneity of WHO grade 4 gliomas: insights from clinical, imaging, and molecular characterization

Abstract Purpose The 2021 WHO classification of central nervous system tumors introduced molecular criteria to stratify Grade 4 gliomas, which remain heterogeneous. This study aims to elucidate the clinical, radiological, and molecular characteristics of WHO Grade 4 gliomas, focusing on their progno...

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Bibliographic Details
Main Authors: Haihui Jiang, Xijie Wang, Xiaodong Chen, Shouzan Zhang, Qingsen Ren, Mingxiao Li, Ming Li, Xiaohui Ren, Song Lin, Yong Cui
Format: Article
Language:English
Published: Springer 2025-02-01
Series:Discover Oncology
Subjects:
Molecular pathology
Glioblastoma
WHO CNS 5
Prognosis
Predictive marker
Online Access:https://doi.org/10.1007/s12672-025-01811-0
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