Modalities for Imaging of Prostate Cancer

Prostate cancer is the second most common cause of cancer deaths among males in the United States. Prostate screening by digital rectal examination and prostate-specific antigen has shifted the diagnosis of prostate cancer to lower grade, organ confined disease, adding to overdetection and overtreat...

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Main Authors: A. H. Hou, D. Swanson, A. B. Barqawi
Format: Article
Language:English
Published: Wiley 2009-01-01
Series:Advances in Urology
Online Access:http://dx.doi.org/10.1155/2009/818065
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author A. H. Hou
D. Swanson
A. B. Barqawi
author_facet A. H. Hou
D. Swanson
A. B. Barqawi
author_sort A. H. Hou
collection DOAJ
description Prostate cancer is the second most common cause of cancer deaths among males in the United States. Prostate screening by digital rectal examination and prostate-specific antigen has shifted the diagnosis of prostate cancer to lower grade, organ confined disease, adding to overdetection and overtreatment of prostate cancer. The new challenge is in differentiating clinically relevant tumors from ones that may otherwise never have become evident if not for screening. The rapid evolution of imaging modalities and the synthesis of anatomic, functional, and molecular data allow for improved detection and characterization of prostate cancer. However, the appropriate use of imaging is difficult to define, as many controversial studies regarding each of the modalities and their utilities can be found in the literature. Clinical practice patterns have been slow to adopt many of these advances as a result. This review discusses the more established imaging techniques, including Ultrasonography, Magnetic Resonance Imaging, MR Spectroscopy, Computed Tomography, and Positron Emission Tomography. We also review several promising techniques on the horizon, including Dynamic Contrast-Enhanced MRI, Diffuse-Weighted Imaging, Superparamagnetic Nanoparticles, and Radionuclide Scintigraphy.
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spelling doaj-art-6f9080b11c2c439a8c613bce9e7e2b7d2025-02-03T01:11:32ZengWileyAdvances in Urology1687-63691687-63772009-01-01200910.1155/2009/818065818065Modalities for Imaging of Prostate CancerA. H. Hou0D. Swanson1A. B. Barqawi2Division of Urology, University of Colorado Health Sciences Center, UCDSOM, MS C-319, Academic Office One Bldg., 12631 East 17th Ave., Room L15-5602, Aurora, CO 80045, USADivision of Urology, University of Colorado Health Sciences Center, UCDSOM, MS C-319, Academic Office One Bldg., 12631 East 17th Ave., Room L15-5602, Aurora, CO 80045, USADivision of Urology, University of Colorado Health Sciences Center, UCDSOM, MS C-319, Academic Office One Bldg., 12631 East 17th Ave., Room L15-5602, Aurora, CO 80045, USAProstate cancer is the second most common cause of cancer deaths among males in the United States. Prostate screening by digital rectal examination and prostate-specific antigen has shifted the diagnosis of prostate cancer to lower grade, organ confined disease, adding to overdetection and overtreatment of prostate cancer. The new challenge is in differentiating clinically relevant tumors from ones that may otherwise never have become evident if not for screening. The rapid evolution of imaging modalities and the synthesis of anatomic, functional, and molecular data allow for improved detection and characterization of prostate cancer. However, the appropriate use of imaging is difficult to define, as many controversial studies regarding each of the modalities and their utilities can be found in the literature. Clinical practice patterns have been slow to adopt many of these advances as a result. This review discusses the more established imaging techniques, including Ultrasonography, Magnetic Resonance Imaging, MR Spectroscopy, Computed Tomography, and Positron Emission Tomography. We also review several promising techniques on the horizon, including Dynamic Contrast-Enhanced MRI, Diffuse-Weighted Imaging, Superparamagnetic Nanoparticles, and Radionuclide Scintigraphy.http://dx.doi.org/10.1155/2009/818065
spellingShingle A. H. Hou
D. Swanson
A. B. Barqawi
Modalities for Imaging of Prostate Cancer
Advances in Urology
title Modalities for Imaging of Prostate Cancer
title_full Modalities for Imaging of Prostate Cancer
title_fullStr Modalities for Imaging of Prostate Cancer
title_full_unstemmed Modalities for Imaging of Prostate Cancer
title_short Modalities for Imaging of Prostate Cancer
title_sort modalities for imaging of prostate cancer
url http://dx.doi.org/10.1155/2009/818065
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