Population pharmacokinetics of iruplinalkib in healthy volunteers and patients with solid tumors

Abstract Iruplinalkib (WX‐0593), a selective oral ALK/ROS1 tyrosine kinase inhibitor, was approved in China as first‐line therapy for ALK‐positive non‐small‐cell lung cancer (NSCLC) and for the treatment of locally advanced or metastatic ALK‐positive NSCLC that has progressed following crizotinib th...

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Bibliographic Details
Main Authors: Guihong Yang, Yimei Wang, Huimin Zhao, Ziyi Jiang, Shansong Zheng, Mingjing Ge, Meimei Si, Xiaoyan Kang
Format: Article
Language:English
Published: Wiley 2025-01-01
Series:Clinical and Translational Science
Online Access:https://doi.org/10.1111/cts.70099
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