Rapidly Polymerizing Click Hydrogel Provides Localized Delivery of rhBMP2 to Promote Bone Formation

Rapidly Polymerizing Click Hydrogel Provides Localized Delivery of rhBMP2 to Promote Bone Formation

ABSTRACT Delivery of bioactive agents to achieve tissue regeneration at targeted sites with minimal side effects requires the use of biodegradable carriers and sustained release of the therapeutic at appropriate concentrations. We developed a copper‐free polyethylene glycol‐based click hydrogel to d...

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Bibliographic Details
Main Authors: D. Joshua Cohen, Thomas W. Jacobs, D. Scott Wilson, Michael C. Mancini, Christine Van Duyn, Zvi Schwartz, Barbara D. Boyan
Format: Article
Language:English
Published: Wiley 2025-06-01
Series:Pharmacology Research & Perspectives
Subjects:
BMP
bone
bone morphogenetic protein‐2
click chemistry
hydrogel
in vitro
Online Access:https://doi.org/10.1002/prp2.70119
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