Clinical Insight into Congenital Hypothyroidism Among Children

Molecular, genetic, and technological advances have led to increased knowledge regarding neonatal thyroid hormone metabolism disorders. Maternal and fetal hypothyroidism, which can cause psychomotor dysfunction syndromes or low IQ levels, can lead to brain damage, reduced fetal growth and incidental...

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Main Author: Hüseyin Anıl Korkmaz
Format: Article
Language:English
Published: MDPI AG 2025-01-01
Series:Children
Subjects:
Online Access:https://www.mdpi.com/2227-9067/12/1/55
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author Hüseyin Anıl Korkmaz
author_facet Hüseyin Anıl Korkmaz
author_sort Hüseyin Anıl Korkmaz
collection DOAJ
description Molecular, genetic, and technological advances have led to increased knowledge regarding neonatal thyroid hormone metabolism disorders. Maternal and fetal hypothyroidism, which can cause psychomotor dysfunction syndromes or low IQ levels, can lead to brain damage, reduced fetal growth and incidental fetal death. The treatment of congenital hypothyroidism detected by screening programs performed during the neonatal period provides normalization of growth, IQ levels, and the physical, mental, and motor development of infants. Therefore, the early diagnosis and treatment of congenital hypothyroidism will prevent the development of complications. In this article, the classification and management of neonatal thyroid diseases are reviewed in light of the current scientific literature.
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spelling doaj-art-6f52a5eee6a2458aa9adc5ddf34302a92025-01-24T13:27:08ZengMDPI AGChildren2227-90672025-01-011215510.3390/children12010055Clinical Insight into Congenital Hypothyroidism Among ChildrenHüseyin Anıl Korkmaz0Department of Pediatrics, Division of Pediatric Endocrinology, Izmir Faculty of Medicine, University of Health Sciences, 35210 Izmir, TurkeyMolecular, genetic, and technological advances have led to increased knowledge regarding neonatal thyroid hormone metabolism disorders. Maternal and fetal hypothyroidism, which can cause psychomotor dysfunction syndromes or low IQ levels, can lead to brain damage, reduced fetal growth and incidental fetal death. The treatment of congenital hypothyroidism detected by screening programs performed during the neonatal period provides normalization of growth, IQ levels, and the physical, mental, and motor development of infants. Therefore, the early diagnosis and treatment of congenital hypothyroidism will prevent the development of complications. In this article, the classification and management of neonatal thyroid diseases are reviewed in light of the current scientific literature.https://www.mdpi.com/2227-9067/12/1/55congenitalhypothyroidismnewbornthyroid gland
spellingShingle Hüseyin Anıl Korkmaz
Clinical Insight into Congenital Hypothyroidism Among Children
Children
congenital
hypothyroidism
newborn
thyroid gland
title Clinical Insight into Congenital Hypothyroidism Among Children
title_full Clinical Insight into Congenital Hypothyroidism Among Children
title_fullStr Clinical Insight into Congenital Hypothyroidism Among Children
title_full_unstemmed Clinical Insight into Congenital Hypothyroidism Among Children
title_short Clinical Insight into Congenital Hypothyroidism Among Children
title_sort clinical insight into congenital hypothyroidism among children
topic congenital
hypothyroidism
newborn
thyroid gland
url https://www.mdpi.com/2227-9067/12/1/55
work_keys_str_mv AT huseyinanılkorkmaz clinicalinsightintocongenitalhypothyroidismamongchildren