IDH-mutant gliomas in children and adolescents - from biology to clinical trials

IDH-mutant gliomas in children and adolescents - from biology to clinical trials

Gliomas account for nearly 30% of all primary central nervous system (CNS) tumors in children and adolescents and young adults (AYA), contributing to significant morbidity and mortality. The updated molecular classification of gliomas defines molecularly diverse subtypes with a spectrum of tumors as...

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Bibliographic Details
Main Authors: Louise Evans, Sarah Trinder, Andrew Dodgshun, David D. Eisenstat, James R. Whittle, Jordan R. Hansford, Santosh Valvi
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Oncology
Subjects:
IDH mutation
low grade glioma
pediatric
adolescent and young adult
AYA
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2024.1515538/full
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