The history, current state and perspectives of aerosol therapy

Nebulization is a very effective method of drug administration. This technique has been popular since ancient times when inhalation of plants rich in tropane alkaloids with spasmolytic and analgesic effects was widely used. Undoubtedly, the invention of anasthesia in the 19th century had an influenc...

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Main Authors: ROSPOND BARTŁOMIEJ, KRAKOWSKA AGATA, MUSZYŃSKA BOŻENA, OPOKA WŁODZIMIERZ
Format: Article
Language:English
Published: Sciendo 2022-06-01
Series:Acta Pharmaceutica
Subjects:
Online Access:https://doi.org/10.2478/acph-2022-0017
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author ROSPOND BARTŁOMIEJ
KRAKOWSKA AGATA
MUSZYŃSKA BOŻENA
OPOKA WŁODZIMIERZ
author_facet ROSPOND BARTŁOMIEJ
KRAKOWSKA AGATA
MUSZYŃSKA BOŻENA
OPOKA WŁODZIMIERZ
author_sort ROSPOND BARTŁOMIEJ
collection DOAJ
description Nebulization is a very effective method of drug administration. This technique has been popular since ancient times when inhalation of plants rich in tropane alkaloids with spasmolytic and analgesic effects was widely used. Undoubtedly, the invention of anasthesia in the 19th century had an influence on the development of this technique. It resulted in the search for devices that facilitated anasthesia such as pulveriser or hydronium. From the second half of the 21st century, when the first DPI and MDI inhalers were launched, the constant development of aerosol therapy has been noticed. This is due to the fact that nebulization, compared with other means of medicinal substance application (such as oral and intravenous routes of administration), is safer and it exhibits a positive dose/efficacy ratio connected to the reduction of the dose. It enables drugs administration through the lung and possesses very fast onset action. Therefore, various drugs prescribed in respiratory diseases (such as corticosteroids, β-agonists, anticholinergics) are present on the market in a form of an aerosol.
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series Acta Pharmaceutica
spelling doaj-art-6f431db7b3e0423eb205f57786e68cce2025-02-02T19:02:00ZengSciendoActa Pharmaceutica1846-95582022-06-0172222524310.2478/acph-2022-0017The history, current state and perspectives of aerosol therapyROSPOND BARTŁOMIEJ0KRAKOWSKA AGATA1MUSZYŃSKA BOŻENA2OPOKA WŁODZIMIERZ31Department of Inorganic and Analytical Chemistry, Faculty of PharmacyJagiellonian University Medical College30-688Kraków, Poland1Department of Inorganic and Analytical Chemistry, Faculty of PharmacyJagiellonian University Medical College30-688Kraków, Poland2Department of Pharmaceutical Botany Faculty of Pharmacy, Jagiellonian University Medical College, 30-688Kraków, Poland1Department of Inorganic and Analytical Chemistry, Faculty of PharmacyJagiellonian University Medical College30-688Kraków, PolandNebulization is a very effective method of drug administration. This technique has been popular since ancient times when inhalation of plants rich in tropane alkaloids with spasmolytic and analgesic effects was widely used. Undoubtedly, the invention of anasthesia in the 19th century had an influence on the development of this technique. It resulted in the search for devices that facilitated anasthesia such as pulveriser or hydronium. From the second half of the 21st century, when the first DPI and MDI inhalers were launched, the constant development of aerosol therapy has been noticed. This is due to the fact that nebulization, compared with other means of medicinal substance application (such as oral and intravenous routes of administration), is safer and it exhibits a positive dose/efficacy ratio connected to the reduction of the dose. It enables drugs administration through the lung and possesses very fast onset action. Therefore, various drugs prescribed in respiratory diseases (such as corticosteroids, β-agonists, anticholinergics) are present on the market in a form of an aerosol.https://doi.org/10.2478/acph-2022-0017inhalationnebulizationplant raw materialsmetered-dose inhalers and dry-powder inhalers
spellingShingle ROSPOND BARTŁOMIEJ
KRAKOWSKA AGATA
MUSZYŃSKA BOŻENA
OPOKA WŁODZIMIERZ
The history, current state and perspectives of aerosol therapy
Acta Pharmaceutica
inhalation
nebulization
plant raw materials
metered-dose inhalers and dry-powder inhalers
title The history, current state and perspectives of aerosol therapy
title_full The history, current state and perspectives of aerosol therapy
title_fullStr The history, current state and perspectives of aerosol therapy
title_full_unstemmed The history, current state and perspectives of aerosol therapy
title_short The history, current state and perspectives of aerosol therapy
title_sort history current state and perspectives of aerosol therapy
topic inhalation
nebulization
plant raw materials
metered-dose inhalers and dry-powder inhalers
url https://doi.org/10.2478/acph-2022-0017
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