TP53 mutation and human papilloma virus status as independent prognostic factors in a Norwegian cohort of vulva squamous cell carcinoma

TP53 mutation and human papilloma virus status as independent prognostic factors in a Norwegian cohort of vulva squamous cell carcinoma

Abstract Introduction Vulva squamous cell carcinoma (VSCC) develops through two separate molecular pathways—one involving high‐risk human papilloma virus infection (HPV‐associated), and the other without HPV infection (HPV‐independent) often involving TP53 mutation. HPV‐associated VSCC generally has...

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Main Authors: Harsh Nitin Dongre, Rammah Elnour, Stian Tornaas, Siren Fromreide, Liv Cecilie Vestrheim Thomsen, Ingrid Benedicte Moss Kolseth, Elisabeth Sivy Nginamau, Anne Christine Johannessen, Olav Karsten Vintermyr, Daniela Elena Costea, Line Bjørge
Format: Article
Language:English
Published: Wiley 2024-01-01
Series:Acta Obstetricia et Gynecologica Scandinavica
Subjects:
human papilloma virus
in situ hybridization
prognosis
TP53
vulva cancer
vulva squamous cell carcinoma
Online Access:https://doi.org/10.1111/aogs.14689
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