Critical role of nosocomial transmission in the Toronto SARS outbreak

We develop a compartmental mathematical model to address therole of hospitals in severe acute respiratory syndrome (SARS) transmissiondynamics, which partially explains the heterogeneity of the epidemic. Comparison of the effects of two major policies, strict hospital infection controlprocedures and...

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Main Authors: Glenn Webb, Martin J. Blaser, Huaiping Zhu, Sten Ardal, Jianhong Wu
Format: Article
Language:English
Published: AIMS Press 2004-02-01
Series:Mathematical Biosciences and Engineering
Subjects:
Online Access:https://www.aimspress.com/article/doi/10.3934/mbe.2004.1.1
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author Glenn Webb
Martin J. Blaser
Huaiping Zhu
Sten Ardal
Jianhong Wu
author_facet Glenn Webb
Martin J. Blaser
Huaiping Zhu
Sten Ardal
Jianhong Wu
author_sort Glenn Webb
collection DOAJ
description We develop a compartmental mathematical model to address therole of hospitals in severe acute respiratory syndrome (SARS) transmissiondynamics, which partially explains the heterogeneity of the epidemic. Comparison of the effects of two major policies, strict hospital infection controlprocedures and community-wide quarantine measures, implemented in Torontotwo weeks into the initial outbreak, shows that their combination is the key toshort-term containment and that quarantine is the key to long-term containment.
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institution Kabale University
issn 1551-0018
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publishDate 2004-02-01
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spelling doaj-art-6f3edc5cf9064f0d8d5e6397c6714c452025-01-24T01:46:28ZengAIMS PressMathematical Biosciences and Engineering1551-00182004-02-011111310.3934/mbe.2004.1.1Critical role of nosocomial transmission in the Toronto SARS outbreakGlenn Webb0Martin J. Blaser1Huaiping Zhu2Sten Ardal3Jianhong Wu4Department of Mathematics, Vanderbilt University, 1326 Stevenson Center, Nashville, TN 37240Department of Medicine, New York University School of Medicine, OBV A606, 550 First Avenue, New York, NY 10016Laboratory for Industrial and Applied Mathematics, Department of Mathematics and Statistics, York University, 4700 Keele Street, Toronto, ON, M3J 1P3Central East Health Information Partnership, Box 159, 4950 Yonge Street, Suite 610, Toronto, ON M2N 6K1Laboratory for Industrial and Applied Mathematics, Department of Mathematics and Statistics, York University, 4700 Keele Street, Toronto, ON, M3J 1P3We develop a compartmental mathematical model to address therole of hospitals in severe acute respiratory syndrome (SARS) transmissiondynamics, which partially explains the heterogeneity of the epidemic. Comparison of the effects of two major policies, strict hospital infection controlprocedures and community-wide quarantine measures, implemented in Torontotwo weeks into the initial outbreak, shows that their combination is the key toshort-term containment and that quarantine is the key to long-term containment.https://www.aimspress.com/article/doi/10.3934/mbe.2004.1.1epidemiologycoronaviruscontainmentquarantine.nonlinear dynamicssevere acute respiratory syndrome (sars)mathematical model
spellingShingle Glenn Webb
Martin J. Blaser
Huaiping Zhu
Sten Ardal
Jianhong Wu
Critical role of nosocomial transmission in the Toronto SARS outbreak
Mathematical Biosciences and Engineering
epidemiology
coronavirus
containment
quarantine.
nonlinear dynamics
severe acute respiratory syndrome (sars)
mathematical model
title Critical role of nosocomial transmission in the Toronto SARS outbreak
title_full Critical role of nosocomial transmission in the Toronto SARS outbreak
title_fullStr Critical role of nosocomial transmission in the Toronto SARS outbreak
title_full_unstemmed Critical role of nosocomial transmission in the Toronto SARS outbreak
title_short Critical role of nosocomial transmission in the Toronto SARS outbreak
title_sort critical role of nosocomial transmission in the toronto sars outbreak
topic epidemiology
coronavirus
containment
quarantine.
nonlinear dynamics
severe acute respiratory syndrome (sars)
mathematical model
url https://www.aimspress.com/article/doi/10.3934/mbe.2004.1.1
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