Critical role of nosocomial transmission in the Toronto SARS outbreak
We develop a compartmental mathematical model to address therole of hospitals in severe acute respiratory syndrome (SARS) transmissiondynamics, which partially explains the heterogeneity of the epidemic. Comparison of the effects of two major policies, strict hospital infection controlprocedures and...
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Language: | English |
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AIMS Press
2004-02-01
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Series: | Mathematical Biosciences and Engineering |
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Online Access: | https://www.aimspress.com/article/doi/10.3934/mbe.2004.1.1 |
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author | Glenn Webb Martin J. Blaser Huaiping Zhu Sten Ardal Jianhong Wu |
author_facet | Glenn Webb Martin J. Blaser Huaiping Zhu Sten Ardal Jianhong Wu |
author_sort | Glenn Webb |
collection | DOAJ |
description | We develop a compartmental mathematical model to address therole of hospitals in severe acute respiratory syndrome (SARS) transmissiondynamics, which partially explains the heterogeneity of the epidemic. Comparison of the effects of two major policies, strict hospital infection controlprocedures and community-wide quarantine measures, implemented in Torontotwo weeks into the initial outbreak, shows that their combination is the key toshort-term containment and that quarantine is the key to long-term containment. |
format | Article |
id | doaj-art-6f3edc5cf9064f0d8d5e6397c6714c45 |
institution | Kabale University |
issn | 1551-0018 |
language | English |
publishDate | 2004-02-01 |
publisher | AIMS Press |
record_format | Article |
series | Mathematical Biosciences and Engineering |
spelling | doaj-art-6f3edc5cf9064f0d8d5e6397c6714c452025-01-24T01:46:28ZengAIMS PressMathematical Biosciences and Engineering1551-00182004-02-011111310.3934/mbe.2004.1.1Critical role of nosocomial transmission in the Toronto SARS outbreakGlenn Webb0Martin J. Blaser1Huaiping Zhu2Sten Ardal3Jianhong Wu4Department of Mathematics, Vanderbilt University, 1326 Stevenson Center, Nashville, TN 37240Department of Medicine, New York University School of Medicine, OBV A606, 550 First Avenue, New York, NY 10016Laboratory for Industrial and Applied Mathematics, Department of Mathematics and Statistics, York University, 4700 Keele Street, Toronto, ON, M3J 1P3Central East Health Information Partnership, Box 159, 4950 Yonge Street, Suite 610, Toronto, ON M2N 6K1Laboratory for Industrial and Applied Mathematics, Department of Mathematics and Statistics, York University, 4700 Keele Street, Toronto, ON, M3J 1P3We develop a compartmental mathematical model to address therole of hospitals in severe acute respiratory syndrome (SARS) transmissiondynamics, which partially explains the heterogeneity of the epidemic. Comparison of the effects of two major policies, strict hospital infection controlprocedures and community-wide quarantine measures, implemented in Torontotwo weeks into the initial outbreak, shows that their combination is the key toshort-term containment and that quarantine is the key to long-term containment.https://www.aimspress.com/article/doi/10.3934/mbe.2004.1.1epidemiologycoronaviruscontainmentquarantine.nonlinear dynamicssevere acute respiratory syndrome (sars)mathematical model |
spellingShingle | Glenn Webb Martin J. Blaser Huaiping Zhu Sten Ardal Jianhong Wu Critical role of nosocomial transmission in the Toronto SARS outbreak Mathematical Biosciences and Engineering epidemiology coronavirus containment quarantine. nonlinear dynamics severe acute respiratory syndrome (sars) mathematical model |
title | Critical role of nosocomial transmission in the Toronto SARS outbreak |
title_full | Critical role of nosocomial transmission in the Toronto SARS outbreak |
title_fullStr | Critical role of nosocomial transmission in the Toronto SARS outbreak |
title_full_unstemmed | Critical role of nosocomial transmission in the Toronto SARS outbreak |
title_short | Critical role of nosocomial transmission in the Toronto SARS outbreak |
title_sort | critical role of nosocomial transmission in the toronto sars outbreak |
topic | epidemiology coronavirus containment quarantine. nonlinear dynamics severe acute respiratory syndrome (sars) mathematical model |
url | https://www.aimspress.com/article/doi/10.3934/mbe.2004.1.1 |
work_keys_str_mv | AT glennwebb criticalroleofnosocomialtransmissioninthetorontosarsoutbreak AT martinjblaser criticalroleofnosocomialtransmissioninthetorontosarsoutbreak AT huaipingzhu criticalroleofnosocomialtransmissioninthetorontosarsoutbreak AT stenardal criticalroleofnosocomialtransmissioninthetorontosarsoutbreak AT jianhongwu criticalroleofnosocomialtransmissioninthetorontosarsoutbreak |