Role of Shear Stress on Renal Proximal Tubular Cells for Nephrotoxicity Assays

Drug-induced nephrotoxicity causes huge morbidity and mortality at massive financial cost. The greatest burden of drug-induced acute kidney injury falls on the proximal tubular cells. To maintain their structure and function, renal proximal tubular cells need the shear stress from tubular fluid flow...

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Bibliographic Details
Main Authors: Holly H. Birdsall, Timothy G. Hammond
Format: Article
Language:English
Published: Wiley 2021-01-01
Series:Journal of Toxicology
Online Access:http://dx.doi.org/10.1155/2021/6643324
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