Role of Shear Stress on Renal Proximal Tubular Cells for Nephrotoxicity Assays
Drug-induced nephrotoxicity causes huge morbidity and mortality at massive financial cost. The greatest burden of drug-induced acute kidney injury falls on the proximal tubular cells. To maintain their structure and function, renal proximal tubular cells need the shear stress from tubular fluid flow...
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Main Authors: | Holly H. Birdsall, Timothy G. Hammond |
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Format: | Article |
Language: | English |
Published: |
Wiley
2021-01-01
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Series: | Journal of Toxicology |
Online Access: | http://dx.doi.org/10.1155/2021/6643324 |
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