Adalimumab‐Induced Cutaneous Lupus Erythematosus: Cases Presenting With Malar Rash and Panniculitis
ABSTRACT Tumor necrosis factor‐alpha (TNF‐α) inhibitors are commonly used for management of various autoimmune disorders but can rarely cause isolated cutaneous lupus. This report presents two cases of cutaneous lupus erythematosus (LE) in women aged 38 and 61 after adalimumab treatment for psoriasi...
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| Format: | Article |
| Language: | English |
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Wiley
2025-01-01
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| Series: | Clinical Case Reports |
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| Online Access: | https://doi.org/10.1002/ccr3.70115 |
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| author | Parvin Mansouri Farahnaz Bidari‐Zerehpoosh Nikoo Mozafari |
| author_facet | Parvin Mansouri Farahnaz Bidari‐Zerehpoosh Nikoo Mozafari |
| author_sort | Parvin Mansouri |
| collection | DOAJ |
| description | ABSTRACT Tumor necrosis factor‐alpha (TNF‐α) inhibitors are commonly used for management of various autoimmune disorders but can rarely cause isolated cutaneous lupus. This report presents two cases of cutaneous lupus erythematosus (LE) in women aged 38 and 61 after adalimumab treatment for psoriasis highlighting the importance of recognizing these paradoxical reactions for timely management. |
| format | Article |
| id | doaj-art-6f36b1a31c5a40908d9bcdb94a37835f |
| institution | Kabale University |
| issn | 2050-0904 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Clinical Case Reports |
| spelling | doaj-art-6f36b1a31c5a40908d9bcdb94a37835f2025-01-24T05:08:46ZengWileyClinical Case Reports2050-09042025-01-01131n/an/a10.1002/ccr3.70115Adalimumab‐Induced Cutaneous Lupus Erythematosus: Cases Presenting With Malar Rash and PanniculitisParvin Mansouri0Farahnaz Bidari‐Zerehpoosh1Nikoo Mozafari2Medical Laser Research Centers, Academic Center of Education, Culture and Research Tehran University of Medical Sciences Tehran IranDepartment of Pathology Loghman‐Hakim Hospital, Shahid Beheshti University of Medical Sciences Tehran IranSkin Research Center Shahid Beheshti University of Medical Sciences Tehran IranABSTRACT Tumor necrosis factor‐alpha (TNF‐α) inhibitors are commonly used for management of various autoimmune disorders but can rarely cause isolated cutaneous lupus. This report presents two cases of cutaneous lupus erythematosus (LE) in women aged 38 and 61 after adalimumab treatment for psoriasis highlighting the importance of recognizing these paradoxical reactions for timely management.https://doi.org/10.1002/ccr3.70115cutaneous lupuslupus panniculitisparadoxical reactionspsoriasistumor necrosis factor‐alpha (TNF‐α) inhibitors |
| spellingShingle | Parvin Mansouri Farahnaz Bidari‐Zerehpoosh Nikoo Mozafari Adalimumab‐Induced Cutaneous Lupus Erythematosus: Cases Presenting With Malar Rash and Panniculitis Clinical Case Reports cutaneous lupus lupus panniculitis paradoxical reactions psoriasis tumor necrosis factor‐alpha (TNF‐α) inhibitors |
| title | Adalimumab‐Induced Cutaneous Lupus Erythematosus: Cases Presenting With Malar Rash and Panniculitis |
| title_full | Adalimumab‐Induced Cutaneous Lupus Erythematosus: Cases Presenting With Malar Rash and Panniculitis |
| title_fullStr | Adalimumab‐Induced Cutaneous Lupus Erythematosus: Cases Presenting With Malar Rash and Panniculitis |
| title_full_unstemmed | Adalimumab‐Induced Cutaneous Lupus Erythematosus: Cases Presenting With Malar Rash and Panniculitis |
| title_short | Adalimumab‐Induced Cutaneous Lupus Erythematosus: Cases Presenting With Malar Rash and Panniculitis |
| title_sort | adalimumab induced cutaneous lupus erythematosus cases presenting with malar rash and panniculitis |
| topic | cutaneous lupus lupus panniculitis paradoxical reactions psoriasis tumor necrosis factor‐alpha (TNF‐α) inhibitors |
| url | https://doi.org/10.1002/ccr3.70115 |
| work_keys_str_mv | AT parvinmansouri adalimumabinducedcutaneouslupuserythematosuscasespresentingwithmalarrashandpanniculitis AT farahnazbidarizerehpoosh adalimumabinducedcutaneouslupuserythematosuscasespresentingwithmalarrashandpanniculitis AT nikoomozafari adalimumabinducedcutaneouslupuserythematosuscasespresentingwithmalarrashandpanniculitis |