A Case of Idiopathic Hypereosinophilic Syndrome Causing Mitral Valve Papillary Muscle Rupture

Idiopathic Hypereosinophilic Syndrome (IHES) is a rare disease that can be difficult to diagnose as the differential is broad. This disease can cause significant morbidity and mortality if left untreated. Our patient is a 17-year-old adolescent female who presented with nonspecific symptoms of abdom...

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Main Authors: Tiffany Tamse, Avind Rampersad, Alejandro Jordan-Villegas, Jill Ireland
Format: Article
Language:English
Published: Wiley 2015-01-01
Series:Case Reports in Pediatrics
Online Access:http://dx.doi.org/10.1155/2015/538762
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author Tiffany Tamse
Avind Rampersad
Alejandro Jordan-Villegas
Jill Ireland
author_facet Tiffany Tamse
Avind Rampersad
Alejandro Jordan-Villegas
Jill Ireland
author_sort Tiffany Tamse
collection DOAJ
description Idiopathic Hypereosinophilic Syndrome (IHES) is a rare disease that can be difficult to diagnose as the differential is broad. This disease can cause significant morbidity and mortality if left untreated. Our patient is a 17-year-old adolescent female who presented with nonspecific symptoms of abdominal pain and malaise. She was incidentally found to have hypereosinophilia of 16,000 on complete blood count and nonspecific colitis and pulmonary edema on computed tomography. She went into cardiogenic shock due to papillary rupture of her mitral valve requiring extreme life support measures including intubation and extracorporal membrane oxygenation (ECMO) as well as mitral valve replacement. Pathology of the valve showed eosinophilic infiltration as the underlying etiology. The patient was diagnosed with IHES after the exclusion of infectious, rheumatologic, and oncologic causes. She was treated with steroids with improvement of her symptoms and scheduled for close follow-up. In general patients with IHES that have cardiac involvement have poorer prognoses.
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spelling doaj-art-6f14be2beab642a9ada602167b984c382025-02-03T01:22:29ZengWileyCase Reports in Pediatrics2090-68032090-68112015-01-01201510.1155/2015/538762538762A Case of Idiopathic Hypereosinophilic Syndrome Causing Mitral Valve Papillary Muscle RuptureTiffany Tamse0Avind Rampersad1Alejandro Jordan-Villegas2Jill Ireland3Florida Hospital for Children, Orlando, FL 32803, USAFlorida Hospital for Children, Orlando, FL 32803, USAFlorida Hospital for Children, Orlando, FL 32803, USAUniversity of Central Florida, Orlando, FL 32827, USAIdiopathic Hypereosinophilic Syndrome (IHES) is a rare disease that can be difficult to diagnose as the differential is broad. This disease can cause significant morbidity and mortality if left untreated. Our patient is a 17-year-old adolescent female who presented with nonspecific symptoms of abdominal pain and malaise. She was incidentally found to have hypereosinophilia of 16,000 on complete blood count and nonspecific colitis and pulmonary edema on computed tomography. She went into cardiogenic shock due to papillary rupture of her mitral valve requiring extreme life support measures including intubation and extracorporal membrane oxygenation (ECMO) as well as mitral valve replacement. Pathology of the valve showed eosinophilic infiltration as the underlying etiology. The patient was diagnosed with IHES after the exclusion of infectious, rheumatologic, and oncologic causes. She was treated with steroids with improvement of her symptoms and scheduled for close follow-up. In general patients with IHES that have cardiac involvement have poorer prognoses.http://dx.doi.org/10.1155/2015/538762
spellingShingle Tiffany Tamse
Avind Rampersad
Alejandro Jordan-Villegas
Jill Ireland
A Case of Idiopathic Hypereosinophilic Syndrome Causing Mitral Valve Papillary Muscle Rupture
Case Reports in Pediatrics
title A Case of Idiopathic Hypereosinophilic Syndrome Causing Mitral Valve Papillary Muscle Rupture
title_full A Case of Idiopathic Hypereosinophilic Syndrome Causing Mitral Valve Papillary Muscle Rupture
title_fullStr A Case of Idiopathic Hypereosinophilic Syndrome Causing Mitral Valve Papillary Muscle Rupture
title_full_unstemmed A Case of Idiopathic Hypereosinophilic Syndrome Causing Mitral Valve Papillary Muscle Rupture
title_short A Case of Idiopathic Hypereosinophilic Syndrome Causing Mitral Valve Papillary Muscle Rupture
title_sort case of idiopathic hypereosinophilic syndrome causing mitral valve papillary muscle rupture
url http://dx.doi.org/10.1155/2015/538762
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