A Survey of Attitudes towards the Clinical Application of Systemic Inflammation Based Prognostic Scores in Cancer
Introduction. The systemic inflammatory response (SIR) plays a key role in determining nutritional status and survival of patients with cancer. A number of objective scoring systems have been shown to have prognostic value; however, their application in routine clinical practice is not clear. The ai...
Saved in:
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2015-01-01
|
| Series: | Mediators of Inflammation |
| Online Access: | http://dx.doi.org/10.1155/2015/842070 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832563918954823680 |
|---|---|
| author | David G. Watt Campbell S. Roxburgh Mark White Juen Zhik Chan Paul G. Horgan Donald C. McMillan |
| author_facet | David G. Watt Campbell S. Roxburgh Mark White Juen Zhik Chan Paul G. Horgan Donald C. McMillan |
| author_sort | David G. Watt |
| collection | DOAJ |
| description | Introduction. The systemic inflammatory response (SIR) plays a key role in determining nutritional status and survival of patients with cancer. A number of objective scoring systems have been shown to have prognostic value; however, their application in routine clinical practice is not clear. The aim of the present survey was to examine the range of opinions internationally on the routine use of these scoring systems. Methods. An online survey was distributed to a target group consisting of individuals worldwide who have reported an interest in systemic inflammation in patients with cancer. Results. Of those invited by the survey (n=238), 65% routinely measured the SIR, mainly for research and prognostication purposes and clinically for allocation of adjuvant therapy or palliative chemotherapy. 40% reported that they currently used the Glasgow Prognostic Score/modified Glasgow Prognostic Score (GPS/mGPS) and 81% reported that a measure of systemic inflammation should be incorporated into clinical guidelines, such as the definition of cachexia. Conclusions. The majority of respondents routinely measured the SIR in patients with cancer, mainly using the GPS/mGPS for research and prognostication purposes. The majority reported that a measure of the SIR should be adopted into clinical guidelines. |
| format | Article |
| id | doaj-art-6f13602b2de945f48a6badea161374e3 |
| institution | Kabale University |
| issn | 0962-9351 1466-1861 |
| language | English |
| publishDate | 2015-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Mediators of Inflammation |
| spelling | doaj-art-6f13602b2de945f48a6badea161374e32025-02-03T01:12:17ZengWileyMediators of Inflammation0962-93511466-18612015-01-01201510.1155/2015/842070842070A Survey of Attitudes towards the Clinical Application of Systemic Inflammation Based Prognostic Scores in CancerDavid G. Watt0Campbell S. Roxburgh1Mark White2Juen Zhik Chan3Paul G. Horgan4Donald C. McMillan5Academic Unit of Surgery, School of Medicine, University of Glasgow, Glasgow Royal Infirmary, Glasgow G31 2ER, UKAcademic Unit of Surgery, School of Medicine, University of Glasgow, Glasgow Royal Infirmary, Glasgow G31 2ER, UKUniversity of Glasgow, Glasgow Medical School, University Avenue, Glasgow G12 8QQ, UKUniversity of Glasgow, Glasgow Medical School, University Avenue, Glasgow G12 8QQ, UKAcademic Unit of Surgery, School of Medicine, University of Glasgow, Glasgow Royal Infirmary, Glasgow G31 2ER, UKAcademic Unit of Surgery, School of Medicine, University of Glasgow, Glasgow Royal Infirmary, Glasgow G31 2ER, UKIntroduction. The systemic inflammatory response (SIR) plays a key role in determining nutritional status and survival of patients with cancer. A number of objective scoring systems have been shown to have prognostic value; however, their application in routine clinical practice is not clear. The aim of the present survey was to examine the range of opinions internationally on the routine use of these scoring systems. Methods. An online survey was distributed to a target group consisting of individuals worldwide who have reported an interest in systemic inflammation in patients with cancer. Results. Of those invited by the survey (n=238), 65% routinely measured the SIR, mainly for research and prognostication purposes and clinically for allocation of adjuvant therapy or palliative chemotherapy. 40% reported that they currently used the Glasgow Prognostic Score/modified Glasgow Prognostic Score (GPS/mGPS) and 81% reported that a measure of systemic inflammation should be incorporated into clinical guidelines, such as the definition of cachexia. Conclusions. The majority of respondents routinely measured the SIR in patients with cancer, mainly using the GPS/mGPS for research and prognostication purposes. The majority reported that a measure of the SIR should be adopted into clinical guidelines.http://dx.doi.org/10.1155/2015/842070 |
| spellingShingle | David G. Watt Campbell S. Roxburgh Mark White Juen Zhik Chan Paul G. Horgan Donald C. McMillan A Survey of Attitudes towards the Clinical Application of Systemic Inflammation Based Prognostic Scores in Cancer Mediators of Inflammation |
| title | A Survey of Attitudes towards the Clinical Application of Systemic Inflammation Based Prognostic Scores in Cancer |
| title_full | A Survey of Attitudes towards the Clinical Application of Systemic Inflammation Based Prognostic Scores in Cancer |
| title_fullStr | A Survey of Attitudes towards the Clinical Application of Systemic Inflammation Based Prognostic Scores in Cancer |
| title_full_unstemmed | A Survey of Attitudes towards the Clinical Application of Systemic Inflammation Based Prognostic Scores in Cancer |
| title_short | A Survey of Attitudes towards the Clinical Application of Systemic Inflammation Based Prognostic Scores in Cancer |
| title_sort | survey of attitudes towards the clinical application of systemic inflammation based prognostic scores in cancer |
| url | http://dx.doi.org/10.1155/2015/842070 |
| work_keys_str_mv | AT davidgwatt asurveyofattitudestowardstheclinicalapplicationofsystemicinflammationbasedprognosticscoresincancer AT campbellsroxburgh asurveyofattitudestowardstheclinicalapplicationofsystemicinflammationbasedprognosticscoresincancer AT markwhite asurveyofattitudestowardstheclinicalapplicationofsystemicinflammationbasedprognosticscoresincancer AT juenzhikchan asurveyofattitudestowardstheclinicalapplicationofsystemicinflammationbasedprognosticscoresincancer AT paulghorgan asurveyofattitudestowardstheclinicalapplicationofsystemicinflammationbasedprognosticscoresincancer AT donaldcmcmillan asurveyofattitudestowardstheclinicalapplicationofsystemicinflammationbasedprognosticscoresincancer AT davidgwatt surveyofattitudestowardstheclinicalapplicationofsystemicinflammationbasedprognosticscoresincancer AT campbellsroxburgh surveyofattitudestowardstheclinicalapplicationofsystemicinflammationbasedprognosticscoresincancer AT markwhite surveyofattitudestowardstheclinicalapplicationofsystemicinflammationbasedprognosticscoresincancer AT juenzhikchan surveyofattitudestowardstheclinicalapplicationofsystemicinflammationbasedprognosticscoresincancer AT paulghorgan surveyofattitudestowardstheclinicalapplicationofsystemicinflammationbasedprognosticscoresincancer AT donaldcmcmillan surveyofattitudestowardstheclinicalapplicationofsystemicinflammationbasedprognosticscoresincancer |