Identify the potential target of efferocytosis in knee osteoarthritis synovial tissue: a bioinformatics and machine learning-based study

Identify the potential target of efferocytosis in knee osteoarthritis synovial tissue: a bioinformatics and machine learning-based study

IntroductionKnee osteoarthritis (KOA) is a degenerative joint disease characterized by the progressive deterioration of cartilage and synovial inflammation. A critical mechanism in the pathogenesis of KOA is impaired efferocytosis in synovial tissue. The present study aimed to identify and validate...

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Main Authors: Shangbo Niu, Mengmeng Li, Jinling Wang, Peirui Zhong, Xing Wen, Fujin Huang, Linwei Yin, Yang Liao, Jun Zhou
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-02-01
Series:Frontiers in Immunology
Subjects:
knee osteoarthritis
efferocytosis-related genes
bioinformatics analysis
machine learning
immune infiltration
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1550794/full
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