A Case of Persistent Bacillus cereus Bacteremia Responding to a Combination of Vancomycin and Gentamicin
A 56-year-old woman with a history of connective tissue disease developed fever, and Bacillus cereus (B. cereus) was detected in blood cultures. Therefore, treatment with vancomycin (VCM) was initiated. Since her blood cultures persistently detected B. cereus despite peripheral intravenous catheter...
Saved in:
| Main Authors: | , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2022-01-01
|
| Series: | Case Reports in Infectious Diseases |
| Online Access: | http://dx.doi.org/10.1155/2022/8725102 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832564060038627328 |
|---|---|
| author | Hiroshi Sasano Toshihiro Yoshizawa Mai Suzuki Yukiko Fukui Ryutarou Arakawa Naoto Tamura Toshio Naito |
| author_facet | Hiroshi Sasano Toshihiro Yoshizawa Mai Suzuki Yukiko Fukui Ryutarou Arakawa Naoto Tamura Toshio Naito |
| author_sort | Hiroshi Sasano |
| collection | DOAJ |
| description | A 56-year-old woman with a history of connective tissue disease developed fever, and Bacillus cereus (B. cereus) was detected in blood cultures. Therefore, treatment with vancomycin (VCM) was initiated. Since her blood cultures persistently detected B. cereus despite peripheral intravenous catheter replacement and VCM treatment, concomitant treatment with gentamicin (GM) was started. Blood cultures then became negative. Persistent B. cereus bacteremia responded to combination therapy with VCM and GM. This combination therapy may increase the risk of developing renal dysfunction, but the risk can be mitigated by appropriate therapeutic drug monitoring (TDM) and dose adjustments to achieve successful treatment. |
| format | Article |
| id | doaj-art-6ed60d90776f4de9b6d0ecce68021e28 |
| institution | Kabale University |
| issn | 2090-6633 |
| language | English |
| publishDate | 2022-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Infectious Diseases |
| spelling | doaj-art-6ed60d90776f4de9b6d0ecce68021e282025-02-03T01:11:56ZengWileyCase Reports in Infectious Diseases2090-66332022-01-01202210.1155/2022/8725102A Case of Persistent Bacillus cereus Bacteremia Responding to a Combination of Vancomycin and GentamicinHiroshi Sasano0Toshihiro Yoshizawa1Mai Suzuki2Yukiko Fukui3Ryutarou Arakawa4Naoto Tamura5Toshio Naito6Department of PharmacyDepartment of PharmacyDepartment of General MedicineDepartment of General MedicineDepartment of PharmacyDepartment of Internal Medicine and RheumatologyDepartment of General MedicineA 56-year-old woman with a history of connective tissue disease developed fever, and Bacillus cereus (B. cereus) was detected in blood cultures. Therefore, treatment with vancomycin (VCM) was initiated. Since her blood cultures persistently detected B. cereus despite peripheral intravenous catheter replacement and VCM treatment, concomitant treatment with gentamicin (GM) was started. Blood cultures then became negative. Persistent B. cereus bacteremia responded to combination therapy with VCM and GM. This combination therapy may increase the risk of developing renal dysfunction, but the risk can be mitigated by appropriate therapeutic drug monitoring (TDM) and dose adjustments to achieve successful treatment.http://dx.doi.org/10.1155/2022/8725102 |
| spellingShingle | Hiroshi Sasano Toshihiro Yoshizawa Mai Suzuki Yukiko Fukui Ryutarou Arakawa Naoto Tamura Toshio Naito A Case of Persistent Bacillus cereus Bacteremia Responding to a Combination of Vancomycin and Gentamicin Case Reports in Infectious Diseases |
| title | A Case of Persistent Bacillus cereus Bacteremia Responding to a Combination of Vancomycin and Gentamicin |
| title_full | A Case of Persistent Bacillus cereus Bacteremia Responding to a Combination of Vancomycin and Gentamicin |
| title_fullStr | A Case of Persistent Bacillus cereus Bacteremia Responding to a Combination of Vancomycin and Gentamicin |
| title_full_unstemmed | A Case of Persistent Bacillus cereus Bacteremia Responding to a Combination of Vancomycin and Gentamicin |
| title_short | A Case of Persistent Bacillus cereus Bacteremia Responding to a Combination of Vancomycin and Gentamicin |
| title_sort | case of persistent bacillus cereus bacteremia responding to a combination of vancomycin and gentamicin |
| url | http://dx.doi.org/10.1155/2022/8725102 |
| work_keys_str_mv | AT hiroshisasano acaseofpersistentbacilluscereusbacteremiarespondingtoacombinationofvancomycinandgentamicin AT toshihiroyoshizawa acaseofpersistentbacilluscereusbacteremiarespondingtoacombinationofvancomycinandgentamicin AT maisuzuki acaseofpersistentbacilluscereusbacteremiarespondingtoacombinationofvancomycinandgentamicin AT yukikofukui acaseofpersistentbacilluscereusbacteremiarespondingtoacombinationofvancomycinandgentamicin AT ryutarouarakawa acaseofpersistentbacilluscereusbacteremiarespondingtoacombinationofvancomycinandgentamicin AT naototamura acaseofpersistentbacilluscereusbacteremiarespondingtoacombinationofvancomycinandgentamicin AT toshionaito acaseofpersistentbacilluscereusbacteremiarespondingtoacombinationofvancomycinandgentamicin AT hiroshisasano caseofpersistentbacilluscereusbacteremiarespondingtoacombinationofvancomycinandgentamicin AT toshihiroyoshizawa caseofpersistentbacilluscereusbacteremiarespondingtoacombinationofvancomycinandgentamicin AT maisuzuki caseofpersistentbacilluscereusbacteremiarespondingtoacombinationofvancomycinandgentamicin AT yukikofukui caseofpersistentbacilluscereusbacteremiarespondingtoacombinationofvancomycinandgentamicin AT ryutarouarakawa caseofpersistentbacilluscereusbacteremiarespondingtoacombinationofvancomycinandgentamicin AT naototamura caseofpersistentbacilluscereusbacteremiarespondingtoacombinationofvancomycinandgentamicin AT toshionaito caseofpersistentbacilluscereusbacteremiarespondingtoacombinationofvancomycinandgentamicin |