Interventions for the management of concomitant COPD and hypertension: A systematic review

Background: Chronic obstructive pulmonary disease (COPD) and hypertension are prevalent public health burdens, with hypertension often co-existing in up to 65% of COPD patients and complicating patient management. While numerous clinical guidelines address these conditions individually, there is a s...

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Main Authors: Sadan Taher, Aletta E. Schutte, John R. Hurst, Chris P. Gale, Sameera Ansari
Format: Article
Language:English
Published: SAGE Publishing 2025-05-01
Series:Journal of Multimorbidity and Comorbidity
Online Access:https://doi.org/10.1177/26335565251341389
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author Sadan Taher
Aletta E. Schutte
John R. Hurst
Chris P. Gale
Sameera Ansari
author_facet Sadan Taher
Aletta E. Schutte
John R. Hurst
Chris P. Gale
Sameera Ansari
author_sort Sadan Taher
collection DOAJ
description Background: Chronic obstructive pulmonary disease (COPD) and hypertension are prevalent public health burdens, with hypertension often co-existing in up to 65% of COPD patients and complicating patient management. While numerous clinical guidelines address these conditions individually, there is a scarcity of evidence-based interventions for managing both simultaneously. Purpose: This systematic review aimed to identify interventional studies targeting people with concomitant COPD and hypertension Research Design: The review followed PRISMA guidelines and was registered on PROSPERO (CRD42024533767). A comprehensive search was conducted across multiple databases, including PubMed, EMBASE, Scopus, CINAHL, the Cochrane Library and Cochrane Controlled Register of Trials. Results: The search yielded 3,348 records, of which three studies met the inclusion criteria. These studies examined interventions including oral nitrate supplementation, medication adherence management and a collaborative care model. One study reported a significant reduction in systolic blood pressure (SBP) and improvement in COPD-related outcomes, while the other two reported mixed effects. The collaborative care model notably reduced hospitalizations and healthcare costs. Conclusions: The findings highlight the limited and inconsistent evidence available for managing concomitant COPD and hypertension, reinforcing the need for further research on this topic. Despite frequent clinical encounters with patients having both conditions, practitioners lack a unified treatment strategy. Future studies should focus on developing comprehensive management approaches that address the complex interplay between COPD and hypertension, aiming to improve patients’ health outcomes and deliver efficient healthcare.
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spelling doaj-art-6ed1e6e56dc74f0c994f2bdbb37e136a2025-08-20T03:29:26ZengSAGE PublishingJournal of Multimorbidity and Comorbidity2633-55652025-05-011510.1177/26335565251341389Interventions for the management of concomitant COPD and hypertension: A systematic reviewSadan TaherAletta E. SchutteJohn R. HurstChris P. GaleSameera AnsariBackground: Chronic obstructive pulmonary disease (COPD) and hypertension are prevalent public health burdens, with hypertension often co-existing in up to 65% of COPD patients and complicating patient management. While numerous clinical guidelines address these conditions individually, there is a scarcity of evidence-based interventions for managing both simultaneously. Purpose: This systematic review aimed to identify interventional studies targeting people with concomitant COPD and hypertension Research Design: The review followed PRISMA guidelines and was registered on PROSPERO (CRD42024533767). A comprehensive search was conducted across multiple databases, including PubMed, EMBASE, Scopus, CINAHL, the Cochrane Library and Cochrane Controlled Register of Trials. Results: The search yielded 3,348 records, of which three studies met the inclusion criteria. These studies examined interventions including oral nitrate supplementation, medication adherence management and a collaborative care model. One study reported a significant reduction in systolic blood pressure (SBP) and improvement in COPD-related outcomes, while the other two reported mixed effects. The collaborative care model notably reduced hospitalizations and healthcare costs. Conclusions: The findings highlight the limited and inconsistent evidence available for managing concomitant COPD and hypertension, reinforcing the need for further research on this topic. Despite frequent clinical encounters with patients having both conditions, practitioners lack a unified treatment strategy. Future studies should focus on developing comprehensive management approaches that address the complex interplay between COPD and hypertension, aiming to improve patients’ health outcomes and deliver efficient healthcare.https://doi.org/10.1177/26335565251341389
spellingShingle Sadan Taher
Aletta E. Schutte
John R. Hurst
Chris P. Gale
Sameera Ansari
Interventions for the management of concomitant COPD and hypertension: A systematic review
Journal of Multimorbidity and Comorbidity
title Interventions for the management of concomitant COPD and hypertension: A systematic review
title_full Interventions for the management of concomitant COPD and hypertension: A systematic review
title_fullStr Interventions for the management of concomitant COPD and hypertension: A systematic review
title_full_unstemmed Interventions for the management of concomitant COPD and hypertension: A systematic review
title_short Interventions for the management of concomitant COPD and hypertension: A systematic review
title_sort interventions for the management of concomitant copd and hypertension a systematic review
url https://doi.org/10.1177/26335565251341389
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