Nucleus Pulposus Cell Conditioned Medium Promotes Mesenchymal Stem Cell Differentiation into Nucleus Pulposus-Like Cells under Hypoxic Conditions

Nucleus Pulposus Cell Conditioned Medium Promotes Mesenchymal Stem Cell Differentiation into Nucleus Pulposus-Like Cells under Hypoxic Conditions

Low back pain (LBP) is a major physical and socioeconomic challenge worldwide. Nucleus pulposus (NP) is directly associated with LBP due to intervertebral disc (IVD) degeneration. IVD degeneration is mainly caused by structural and matrix-related changes within the IVD occurring during aging and deg...

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Bibliographic Details
Main Authors:	Arjun Sinkemani, Feng Wang, Zhiyang Xie, Lu Chen, Cong Zhang, Xiaotao Wu
Format:	Article
Language:	English
Published:	Wiley 2020-01-01
Series:	Stem Cells International
Online Access:	http://dx.doi.org/10.1155/2020/8882549
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