The southern house mosquito Culex quinquefasciatus in Abu Dhabi, UAE, is developing resistance to deltamethrin insecticide
Abstract Culex quinquefasciatus is a widely spread mosquito species that poses a significant public health threat in many countries. This insect vector is present in the United Arab Emirates (UAE), yet no studies have been conducted on its resistance to any insecticide group. Research shows that con...
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Nature Portfolio
2025-01-01
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| Online Access: | https://doi.org/10.1038/s41598-025-87843-6 |
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| author | Amgd sayed Ali Asim Iqbal Tamilarasan Kamalanathan Antony Raj Gnanaprakasam Sabu Shajahan Mohammad Hamad Alsadeq Mohamed Mahmood Al Marzooqi Mohamad Hamdan Mohammad Ali Al-Deeb |
| author_facet | Amgd sayed Ali Asim Iqbal Tamilarasan Kamalanathan Antony Raj Gnanaprakasam Sabu Shajahan Mohammad Hamad Alsadeq Mohamed Mahmood Al Marzooqi Mohamad Hamdan Mohammad Ali Al-Deeb |
| author_sort | Amgd sayed Ali |
| collection | DOAJ |
| description | Abstract Culex quinquefasciatus is a widely spread mosquito species that poses a significant public health threat in many countries. This insect vector is present in the United Arab Emirates (UAE), yet no studies have been conducted on its resistance to any insecticide group. Research shows that controlling mosquitoes is crucial to eliminating mosquito-borne diseases, but when these vectors develop insecticide resistance, the situation can escalate dangerously out of control. This study aimed to identify a knockdown resistance (kdr) mutation L1014F using molecular tools. Additionally, it aimed to assess deltamethrin resistance using the Centers for Disease Control and Prevention (CDC) bottle bioassay. We screened Cx. quinquefasciatus adults (N = 174) for the presence of the mutation using allele-specific PCR (AS-PCR) and DNA sequencing. We detected the mutation and found the kdr allele in all the sampled locations. Furthermore, the CDC bottle bioassay revealed deltamethrin resistance from only one sampling location. To our knowledge, this is the first report of insecticide resistance in Cx. quinquefasciatus in the UAE. Our findings show the need for continued insecticide resistance monitoring for effective mosquito control in the UAE. |
| format | Article |
| id | doaj-art-6eca5ac190664fe784f6a79bad0306df |
| institution | Kabale University |
| issn | 2045-2322 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Nature Portfolio |
| record_format | Article |
| series | Scientific Reports |
| spelling | doaj-art-6eca5ac190664fe784f6a79bad0306df2025-02-02T12:18:06ZengNature PortfolioScientific Reports2045-23222025-01-0115111310.1038/s41598-025-87843-6The southern house mosquito Culex quinquefasciatus in Abu Dhabi, UAE, is developing resistance to deltamethrin insecticideAmgd sayed Ali0Asim Iqbal1Tamilarasan Kamalanathan2Antony Raj Gnanaprakasam3Sabu Shajahan4Mohammad Hamad Alsadeq5Mohamed Mahmood Al Marzooqi6Mohamad Hamdan7Mohammad Ali Al-Deeb8Biology Department, UAE UniversityPest Control Department, Abu Dhabi Public Health Center (ADPHC)Pest Control Department, Abu Dhabi Public Health Center (ADPHC)Pest Control Department, Abu Dhabi Public Health Center (ADPHC)Pest Control Department, Abu Dhabi Public Health Center (ADPHC)Pest Control Department, Abu Dhabi Public Health Center (ADPHC)Pest Control Department, Abu Dhabi Public Health Center (ADPHC)Biology Department, UAE UniversityBiology Department, UAE UniversityAbstract Culex quinquefasciatus is a widely spread mosquito species that poses a significant public health threat in many countries. This insect vector is present in the United Arab Emirates (UAE), yet no studies have been conducted on its resistance to any insecticide group. Research shows that controlling mosquitoes is crucial to eliminating mosquito-borne diseases, but when these vectors develop insecticide resistance, the situation can escalate dangerously out of control. This study aimed to identify a knockdown resistance (kdr) mutation L1014F using molecular tools. Additionally, it aimed to assess deltamethrin resistance using the Centers for Disease Control and Prevention (CDC) bottle bioassay. We screened Cx. quinquefasciatus adults (N = 174) for the presence of the mutation using allele-specific PCR (AS-PCR) and DNA sequencing. We detected the mutation and found the kdr allele in all the sampled locations. Furthermore, the CDC bottle bioassay revealed deltamethrin resistance from only one sampling location. To our knowledge, this is the first report of insecticide resistance in Cx. quinquefasciatus in the UAE. Our findings show the need for continued insecticide resistance monitoring for effective mosquito control in the UAE.https://doi.org/10.1038/s41598-025-87843-6Culex quinquefasciatusPyrethroidDeltamethrinkdrResistanceAS-PCR |
| spellingShingle | Amgd sayed Ali Asim Iqbal Tamilarasan Kamalanathan Antony Raj Gnanaprakasam Sabu Shajahan Mohammad Hamad Alsadeq Mohamed Mahmood Al Marzooqi Mohamad Hamdan Mohammad Ali Al-Deeb The southern house mosquito Culex quinquefasciatus in Abu Dhabi, UAE, is developing resistance to deltamethrin insecticide Scientific Reports Culex quinquefasciatus Pyrethroid Deltamethrin kdr Resistance AS-PCR |
| title | The southern house mosquito Culex quinquefasciatus in Abu Dhabi, UAE, is developing resistance to deltamethrin insecticide |
| title_full | The southern house mosquito Culex quinquefasciatus in Abu Dhabi, UAE, is developing resistance to deltamethrin insecticide |
| title_fullStr | The southern house mosquito Culex quinquefasciatus in Abu Dhabi, UAE, is developing resistance to deltamethrin insecticide |
| title_full_unstemmed | The southern house mosquito Culex quinquefasciatus in Abu Dhabi, UAE, is developing resistance to deltamethrin insecticide |
| title_short | The southern house mosquito Culex quinquefasciatus in Abu Dhabi, UAE, is developing resistance to deltamethrin insecticide |
| title_sort | southern house mosquito culex quinquefasciatus in abu dhabi uae is developing resistance to deltamethrin insecticide |
| topic | Culex quinquefasciatus Pyrethroid Deltamethrin kdr Resistance AS-PCR |
| url | https://doi.org/10.1038/s41598-025-87843-6 |
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