Reduced gap junction coupling amplifies the effects of cardiomyocyte variability and destabilizes the heartbeat

Abstract Cardiomyocytes exhibit significant cell‐to‐cell variability due to differences in protein expression and post‐translational modifications in the cell membrane and the intracellular machinery. Resulting variability in action potential propagation and configuration is proposed to promote arrh...

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Bibliographic Details
Main Authors: Karoline Horgmo Jæger, William E. Louch, Aslak Tveito
Format: Article
Language:English
Published: Wiley 2025-07-01
Series:Physiological Reports
Subjects:
Online Access:https://doi.org/10.14814/phy2.70461
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