No Weight Catch-Up Growth of SGA Infants Is Associated with Impaired Insulin Sensitivity during the Early Postnatal Period
Objective. To investigate the relationship between weight catch-up growth and insulin sensitivity in small for gestational age (SGA) infants. Methods. Forty-four singleton SGA subjects met the inclusion criteria and finished-3-month followup. Body weight, length, fasting glucose, and fasting insulin...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2010-01-01
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| Series: | International Journal of Pediatrics |
| Online Access: | http://dx.doi.org/10.1155/2010/704642 |
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| _version_ | 1832564690078662656 |
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| author | Tong-yan Han Xin-li Wang Yun-pu Cui Hong-mao Ye Xiao-mei Tong Mei-hua Piao |
| author_facet | Tong-yan Han Xin-li Wang Yun-pu Cui Hong-mao Ye Xiao-mei Tong Mei-hua Piao |
| author_sort | Tong-yan Han |
| collection | DOAJ |
| description | Objective. To investigate the relationship between weight catch-up growth and insulin sensitivity in small for gestational age (SGA) infants. Methods. Forty-four singleton SGA subjects met the inclusion criteria and finished-3-month followup. Body weight, length, fasting glucose, and fasting insulin (FI) levels were measured at 3 days and 3 months. Insulin sensitivity was evaluated by FI and homeostasis model assessment (HOMA). Results. According to the change of weight Z-score, forty-four subjects were divided into two groups: noncatch-up growth (NCUG) and catch-up growth (CUG). By 3 months of age, the body weight, body length and BMI of NCUG group were significantly lower than those of CUG group. The FI and HOMA were significantly higher in NCUG group. The change of weight Z-score during 3 months was inversely related to the HOMA at 3 months. Conclusion. Our data exemplified that no weight catch-up growth during the first 3 months was associated with impaired insulin sensitivity in SGA infants. |
| format | Article |
| id | doaj-art-6ea19e5b1aec4948a0dcd6eb2b5029dc |
| institution | Kabale University |
| issn | 1687-9740 1687-9759 |
| language | English |
| publishDate | 2010-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Pediatrics |
| spelling | doaj-art-6ea19e5b1aec4948a0dcd6eb2b5029dc2025-02-03T01:10:31ZengWileyInternational Journal of Pediatrics1687-97401687-97592010-01-01201010.1155/2010/704642704642No Weight Catch-Up Growth of SGA Infants Is Associated with Impaired Insulin Sensitivity during the Early Postnatal PeriodTong-yan Han0Xin-li Wang1Yun-pu Cui2Hong-mao Ye3Xiao-mei Tong4Mei-hua Piao5Department of Pediatrics, Peking University Third Hospital, Beijing 100083, ChinaDepartment of Pediatrics, Peking University Third Hospital, Beijing 100083, ChinaDepartment of Pediatrics, Peking University Third Hospital, Beijing 100083, ChinaDepartment of Pediatrics, Peking University Third Hospital, Beijing 100083, ChinaDepartment of Pediatrics, Peking University Third Hospital, Beijing 100083, ChinaDepartment of Pediatrics, Peking University Third Hospital, Beijing 100083, ChinaObjective. To investigate the relationship between weight catch-up growth and insulin sensitivity in small for gestational age (SGA) infants. Methods. Forty-four singleton SGA subjects met the inclusion criteria and finished-3-month followup. Body weight, length, fasting glucose, and fasting insulin (FI) levels were measured at 3 days and 3 months. Insulin sensitivity was evaluated by FI and homeostasis model assessment (HOMA). Results. According to the change of weight Z-score, forty-four subjects were divided into two groups: noncatch-up growth (NCUG) and catch-up growth (CUG). By 3 months of age, the body weight, body length and BMI of NCUG group were significantly lower than those of CUG group. The FI and HOMA were significantly higher in NCUG group. The change of weight Z-score during 3 months was inversely related to the HOMA at 3 months. Conclusion. Our data exemplified that no weight catch-up growth during the first 3 months was associated with impaired insulin sensitivity in SGA infants.http://dx.doi.org/10.1155/2010/704642 |
| spellingShingle | Tong-yan Han Xin-li Wang Yun-pu Cui Hong-mao Ye Xiao-mei Tong Mei-hua Piao No Weight Catch-Up Growth of SGA Infants Is Associated with Impaired Insulin Sensitivity during the Early Postnatal Period International Journal of Pediatrics |
| title | No Weight Catch-Up Growth of SGA Infants Is Associated with Impaired Insulin Sensitivity during the Early Postnatal Period |
| title_full | No Weight Catch-Up Growth of SGA Infants Is Associated with Impaired Insulin Sensitivity during the Early Postnatal Period |
| title_fullStr | No Weight Catch-Up Growth of SGA Infants Is Associated with Impaired Insulin Sensitivity during the Early Postnatal Period |
| title_full_unstemmed | No Weight Catch-Up Growth of SGA Infants Is Associated with Impaired Insulin Sensitivity during the Early Postnatal Period |
| title_short | No Weight Catch-Up Growth of SGA Infants Is Associated with Impaired Insulin Sensitivity during the Early Postnatal Period |
| title_sort | no weight catch up growth of sga infants is associated with impaired insulin sensitivity during the early postnatal period |
| url | http://dx.doi.org/10.1155/2010/704642 |
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