Efficacy and safety of oral amantadine in Parkinson’s disease with dyskinesia and motor fluctuations: a systematic review and meta-analysis of randomised controlled trials

Background Oral amantadine is available in three formulations with distinct pharmacokinetics: immediate-release (IR), delayed-release/extended-release (DR/ER) and immediate-release/extended-release (IR/ER). While all formulations alleviate levodopa-induced dyskinesia, only DR/ER has shown efficacy f...

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Bibliographic Details
Main Authors: Surachet Rujirussawarawong, Saharat Aungsumart, Chayut Kasemsuk, Natlada Limotai
Format: Article
Language:English
Published: BMJ Publishing Group 2025-06-01
Series:BMJ Neurology Open
Online Access:https://neurologyopen.bmj.com/content/7/1/e001115.full
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