Endothelial dysfunction in congenital adrenal hyperplasia due to 21-hydroxylase deficiency: current knowledge and novel biomarkers

Endothelial dysfunction in congenital adrenal hyperplasia due to 21-hydroxylase deficiency: current knowledge and novel biomarkers

Congenital adrenal hyperplasia (CAH) due to 21-hydroxylase deficiency (21OHD) is a complex endocrine disorder characterized by impaired cortisol synthesis and androgen excess. Beyond its hormonal and metabolic implications, CAH has been increasingly associated with an elevated risk of cardiovascular...

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Bibliographic Details
Main Authors: Joanna Hubska, Zuzanna Roszkowska, Małgorzata Bobrowicz, Sebastian Iwaniuk, Beata Rak-Makowska, Urszula Ambroziak
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Endocrinology
Subjects:
congenital adrenal hyperplasia (CAH)
21-hydroxylase deficiency
endothelial dysfunction
endothelial biomarkers
cardiovascular disease
cardiovascular risk
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2025.1581681/full
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