Disease Specific to Chronic Lymphedema and Class III Obesity
Elephantiasis nostras verrucosa (ENV) is a unique, chronic condition found in patients with obesity and chronic secondary lymphedema. It develops due to chronic inflammation and recurrent infection, most commonly on gravity-dependent sites. Progressive tissue enlargement, deformity, and disability n...
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| Format: | Article |
| Language: | English |
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Wiley
2020-01-01
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| Series: | Case Reports in Medicine |
| Online Access: | http://dx.doi.org/10.1155/2020/9234183 |
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| author | Karen G. Figenshau Matthew B. Lindquist |
| author_facet | Karen G. Figenshau Matthew B. Lindquist |
| author_sort | Karen G. Figenshau |
| collection | DOAJ |
| description | Elephantiasis nostras verrucosa (ENV) is a unique, chronic condition found in patients with obesity and chronic secondary lymphedema. It develops due to chronic inflammation and recurrent infection, most commonly on gravity-dependent sites. Progressive tissue enlargement, deformity, and disability necessitate intervention. First, clinicians should explore the etiology of patients’ secondary lymphedema, as this is paramount in determining treatment for ENV. The fundamental goal is alleviating lymphatic obstruction. Our literature review of available cases of ENV elucidates Class III obesity as a factor common to all available cases of ENV. As such, weight loss is a key component of treatment. Medical management and weight loss are most effective when combined with physiologic interventions such as compression garments and decongestive physiotherapy. If surgical intervention is required, one of the mainstays of patient management is a reductive approach, aimed at removing excess adipose and fibrotic tissue to improve lymphatic patency and flow. Optimal postoperative outcomes are achieved when patients also undergo physiologic procedures to bypass obstructions and connect functioning lymphatic vessels. |
| format | Article |
| id | doaj-art-6e67bb61b4b042cf8106ff7d55662b5b |
| institution | Kabale University |
| issn | 1687-9627 1687-9635 |
| language | English |
| publishDate | 2020-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Medicine |
| spelling | doaj-art-6e67bb61b4b042cf8106ff7d55662b5b2025-02-03T05:51:45ZengWileyCase Reports in Medicine1687-96271687-96352020-01-01202010.1155/2020/92341839234183Disease Specific to Chronic Lymphedema and Class III ObesityKaren G. Figenshau0Matthew B. Lindquist1University of Missouri Kansas City School of Medicine, Kansas City 64108, USADepartment of Internal Medicine, University of Missouri Kansas City School of Medicine, Kansas City 64108, USAElephantiasis nostras verrucosa (ENV) is a unique, chronic condition found in patients with obesity and chronic secondary lymphedema. It develops due to chronic inflammation and recurrent infection, most commonly on gravity-dependent sites. Progressive tissue enlargement, deformity, and disability necessitate intervention. First, clinicians should explore the etiology of patients’ secondary lymphedema, as this is paramount in determining treatment for ENV. The fundamental goal is alleviating lymphatic obstruction. Our literature review of available cases of ENV elucidates Class III obesity as a factor common to all available cases of ENV. As such, weight loss is a key component of treatment. Medical management and weight loss are most effective when combined with physiologic interventions such as compression garments and decongestive physiotherapy. If surgical intervention is required, one of the mainstays of patient management is a reductive approach, aimed at removing excess adipose and fibrotic tissue to improve lymphatic patency and flow. Optimal postoperative outcomes are achieved when patients also undergo physiologic procedures to bypass obstructions and connect functioning lymphatic vessels.http://dx.doi.org/10.1155/2020/9234183 |
| spellingShingle | Karen G. Figenshau Matthew B. Lindquist Disease Specific to Chronic Lymphedema and Class III Obesity Case Reports in Medicine |
| title | Disease Specific to Chronic Lymphedema and Class III Obesity |
| title_full | Disease Specific to Chronic Lymphedema and Class III Obesity |
| title_fullStr | Disease Specific to Chronic Lymphedema and Class III Obesity |
| title_full_unstemmed | Disease Specific to Chronic Lymphedema and Class III Obesity |
| title_short | Disease Specific to Chronic Lymphedema and Class III Obesity |
| title_sort | disease specific to chronic lymphedema and class iii obesity |
| url | http://dx.doi.org/10.1155/2020/9234183 |
| work_keys_str_mv | AT karengfigenshau diseasespecifictochroniclymphedemaandclassiiiobesity AT matthewblindquist diseasespecifictochroniclymphedemaandclassiiiobesity |