Testicular Inflammatory Myofibroblastic Tumor: A Known Entity at a Very Rare Site

Inflammatory myofibroblastic tumors (IMT) are distinctive lesions of unknown etiology, composed of myofibroblastic spindle cells with an associated inflammatory background. They can occur in a wide age range and at all anatomic sites, but most frequently they can be observed in the lung (especially...

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Main Authors: Hans-Ullrich Voelker, Daniel Kuehn, Annette Strehl, Stefan Kircher
Format: Article
Language:English
Published: Wiley 2017-01-01
Series:Case Reports in Urology
Online Access:http://dx.doi.org/10.1155/2017/1410843
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author Hans-Ullrich Voelker
Daniel Kuehn
Annette Strehl
Stefan Kircher
author_facet Hans-Ullrich Voelker
Daniel Kuehn
Annette Strehl
Stefan Kircher
author_sort Hans-Ullrich Voelker
collection DOAJ
description Inflammatory myofibroblastic tumors (IMT) are distinctive lesions of unknown etiology, composed of myofibroblastic spindle cells with an associated inflammatory background. They can occur in a wide age range and at all anatomic sites, but most frequently they can be observed in the lung (especially in pediatric cases), abdomen, or retroperitoneum. The urinary bladder is one of the most common sites in urological cases. We present a very rare case of IMT of the testis. Clinically, a 40-year-old patient showed a palpable painless lesion of the right testis. Ultrasound examination showed two solid intratesticular foci. During surgical intervention, the intraoperative frozen section revealed mesenchymal tumors admixed with an uncommon inflammatory infiltrate, consistent with a reorganized abscess. Despite the benign result, orchiectomy was performed due to the multifocal presentation and the large size of 3 cm. The final diagnosis was IMT without ALK-rearrangement. Incomplete resection increases the risk of local relapses to 30%. In this case, a complete resection could be achieved and the patient is free of tumor 15 months later.
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institution Kabale University
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language English
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series Case Reports in Urology
spelling doaj-art-6e4a4bb48b4c4e8b9d052d252ff85ab12025-08-20T03:33:56ZengWileyCase Reports in Urology2090-696X2090-69782017-01-01201710.1155/2017/14108431410843Testicular Inflammatory Myofibroblastic Tumor: A Known Entity at a Very Rare SiteHans-Ullrich Voelker0Daniel Kuehn1Annette Strehl2Stefan Kircher3Institute of Pathology, Leopoldina Hospital, 97422 Schweinfurt, GermanyDepartment of Urology, Leopoldina Hospital, 97422 Schweinfurt, GermanyInstitute of Pathology, Leopoldina Hospital, 97422 Schweinfurt, GermanyInstitute of Pathology, University of Wuerzburg, 97080 Wuerzburg, GermanyInflammatory myofibroblastic tumors (IMT) are distinctive lesions of unknown etiology, composed of myofibroblastic spindle cells with an associated inflammatory background. They can occur in a wide age range and at all anatomic sites, but most frequently they can be observed in the lung (especially in pediatric cases), abdomen, or retroperitoneum. The urinary bladder is one of the most common sites in urological cases. We present a very rare case of IMT of the testis. Clinically, a 40-year-old patient showed a palpable painless lesion of the right testis. Ultrasound examination showed two solid intratesticular foci. During surgical intervention, the intraoperative frozen section revealed mesenchymal tumors admixed with an uncommon inflammatory infiltrate, consistent with a reorganized abscess. Despite the benign result, orchiectomy was performed due to the multifocal presentation and the large size of 3 cm. The final diagnosis was IMT without ALK-rearrangement. Incomplete resection increases the risk of local relapses to 30%. In this case, a complete resection could be achieved and the patient is free of tumor 15 months later.http://dx.doi.org/10.1155/2017/1410843
spellingShingle Hans-Ullrich Voelker
Daniel Kuehn
Annette Strehl
Stefan Kircher
Testicular Inflammatory Myofibroblastic Tumor: A Known Entity at a Very Rare Site
Case Reports in Urology
title Testicular Inflammatory Myofibroblastic Tumor: A Known Entity at a Very Rare Site
title_full Testicular Inflammatory Myofibroblastic Tumor: A Known Entity at a Very Rare Site
title_fullStr Testicular Inflammatory Myofibroblastic Tumor: A Known Entity at a Very Rare Site
title_full_unstemmed Testicular Inflammatory Myofibroblastic Tumor: A Known Entity at a Very Rare Site
title_short Testicular Inflammatory Myofibroblastic Tumor: A Known Entity at a Very Rare Site
title_sort testicular inflammatory myofibroblastic tumor a known entity at a very rare site
url http://dx.doi.org/10.1155/2017/1410843
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AT danielkuehn testicularinflammatorymyofibroblastictumoraknownentityataveryraresite
AT annettestrehl testicularinflammatorymyofibroblastictumoraknownentityataveryraresite
AT stefankircher testicularinflammatorymyofibroblastictumoraknownentityataveryraresite