Activation of SIRT3 / PRDX5 signaling inhibits apoptosis after acute spinal cord injury in mice

Activation of SIRT3 / PRDX5 signaling inhibits apoptosis after acute spinal cord injury in mice

Spinal cord injury (SCI), a traumatic condition affecting the nervous system, constitutes an orthopedic emergency that is closely associated with a significantly elevated disability rate. Excessive apoptosis not only hinders neuronal repair, but also exacerbates the deterioration of the local microe...

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Bibliographic Details
Main Authors: Hui Ni, Weiping Sha, Tianli Xu, Qiancheng Zhu, Qun Huang, Jin Wang, Qi Gu, Yi Zhu, Liming Wang, Shoujin Tian, Rong Gao, Jianfei Ge, Xiaolong Lin
Format: Article
Language:English
Published: Elsevier 2025-10-01
Series:Brain Research Bulletin
Subjects:
SIRT3
PRDX5
Spinal cord injury
Neuroprotection
Apoptosis
Online Access:http://www.sciencedirect.com/science/article/pii/S0361923025003223
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