Development of a MaizeGerm50K array and application to maize genetic studies and breeding

Development of a MaizeGerm50K array and application to maize genetic studies and breeding

Genotyping arrays based on single nucleotide polymorphisms (SNPs) provide a low-cost, high-throughput platform. The development of a SNP array that fully reflects the genetic diversity of maize (Zea mays L.) germplasm and is applicable to molecular breeding programs is desirable. In this study, we d...

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Bibliographic Details
Main Authors: Honghui Guan, Yaxuan Lu, Xinchun Li, Bei Liu, Yongxiang Li, Dengfeng Zhang, Xuyang Liu, Guanhua He, Yu Li, Hongwu Wang, Tianyu Wang, Chunhui Li
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2024-12-01
Series:Crop Journal
Subjects:
Maize
Genotyping
Liquid array
Single nucleotide polymorphism (SNP)
Molecular breeding
Online Access:http://www.sciencedirect.com/science/article/pii/S2214514124001958
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Summary:Genotyping arrays based on single nucleotide polymorphisms (SNPs) provide a low-cost, high-throughput platform. The development of a SNP array that fully reflects the genetic diversity of maize (Zea mays L.) germplasm and is applicable to molecular breeding programs is desirable. In this study, we developed a MaizeGerm50K array comprising 50,852 SNPs selected from the resequencing data of 1604 maize inbred lines and other markers. A genome-wide association study using a landrace panel genotyped with the array permitted mapping of several known genes. We also verified a candidate gene, RNA-binding motif protein 24-like 1 (ZmRBM24L1), delaying flowering through overexpression lines. Genomic selection for yield and agronomic traits showed high prediction accuracy. The MaizeGerm50K array is thus a valuable genomic tool for maize genetic studies and breeding.
ISSN:2214-5141

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