Insulin Resistance: A Proinflammatory State Mediated by Lipid-Induced Signaling Dysfunction and Involved in Atherosclerotic Plaque Instability

The dysregulation of the insulin-glucose axis represents the crucial event in insulin resistance syndrome. Insulin resistance increases atherogenesis and atherosclerotic plaque instability by inducing proinflammatory activities on vascular and immune cells. This condition characterizes several disea...

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Bibliographic Details
Main Authors: Fabrizio Montecucco, Sabine Steffens, François Mach
Format: Article
Language:English
Published: Wiley 2008-01-01
Series:Mediators of Inflammation
Online Access:http://dx.doi.org/10.1155/2008/767623
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