Epidemiology and Trends of Cutaneous Fungal Infections (2019–2022) in Israel: A Single Tertiary-Center Study
Cutaneous fungal infections predominantly caused by dermatophytes are a global concern. These infections vary widely by region, age, and body site, with recent shifts in the pathogen distribution. This study examines the distribution and trends of superficial fungal infections in a large tertiary ca...
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| Format: | Article |
| Language: | English |
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MDPI AG
2025-04-01
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| Series: | Journal of Fungi |
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| Online Access: | https://www.mdpi.com/2309-608X/11/4/320 |
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| author | Eran Galili Auriella Taieb Avner Shemer Gil Leor Anna Lyakhovitsky Aviv Barzilai Sharon Baum |
| author_facet | Eran Galili Auriella Taieb Avner Shemer Gil Leor Anna Lyakhovitsky Aviv Barzilai Sharon Baum |
| author_sort | Eran Galili |
| collection | DOAJ |
| description | Cutaneous fungal infections predominantly caused by dermatophytes are a global concern. These infections vary widely by region, age, and body site, with recent shifts in the pathogen distribution. This study examines the distribution and trends of superficial fungal infections in a large tertiary care center in Israel from 2019 to 2022. A retrospective analysis of 2244 patients with suspected fungal infections was performed, utilizing PCR and fungal cultures for diagnosis. Confirmed fungal infections were present in 53.0% of cases. In adults, infections predominantly affected the nails and feet, while in children, the scalp and nails were the most involved sites. <i>Trichophyton rubrum</i> was the most common pathogen overall, but <i>T. tonsurans</i> was the leading cause of scalp, face, and neck infections, as well as tinea corporis in children. <i>T. tonsurans</i> incidence significantly increased in adults and became the most frequent agent of upper-body tinea corporis by 2022. These findings highlight a shift in pathogen distribution, with <i>T. tonsurans</i> emerging as the leading cause of upper-body skin infections, underscoring the need for targeted prevention strategies and further investigation of its transmission routes. |
| format | Article |
| id | doaj-art-6de04ece4d424bb09b3e31cfcedc8e33 |
| institution | OA Journals |
| issn | 2309-608X |
| language | English |
| publishDate | 2025-04-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Journal of Fungi |
| spelling | doaj-art-6de04ece4d424bb09b3e31cfcedc8e332025-08-20T02:28:32ZengMDPI AGJournal of Fungi2309-608X2025-04-0111432010.3390/jof11040320Epidemiology and Trends of Cutaneous Fungal Infections (2019–2022) in Israel: A Single Tertiary-Center StudyEran Galili0Auriella Taieb1Avner Shemer2Gil Leor3Anna Lyakhovitsky4Aviv Barzilai5Sharon Baum6Department of Dermatology, Sheba Medical Center, Ramat-Gan 52621, IsraelDepartment of Dermatology, Sheba Medical Center, Ramat-Gan 52621, IsraelDepartment of Dermatology, Sheba Medical Center, Ramat-Gan 52621, IsraelFaculty of Medicine and Health Sciences, Tel Aviv University, Tel Aviv 69978, IsraelDepartment of Dermatology, Sheba Medical Center, Ramat-Gan 52621, IsraelDepartment of Dermatology, Sheba Medical Center, Ramat-Gan 52621, IsraelDepartment of Dermatology, Sheba Medical Center, Ramat-Gan 52621, IsraelCutaneous fungal infections predominantly caused by dermatophytes are a global concern. These infections vary widely by region, age, and body site, with recent shifts in the pathogen distribution. This study examines the distribution and trends of superficial fungal infections in a large tertiary care center in Israel from 2019 to 2022. A retrospective analysis of 2244 patients with suspected fungal infections was performed, utilizing PCR and fungal cultures for diagnosis. Confirmed fungal infections were present in 53.0% of cases. In adults, infections predominantly affected the nails and feet, while in children, the scalp and nails were the most involved sites. <i>Trichophyton rubrum</i> was the most common pathogen overall, but <i>T. tonsurans</i> was the leading cause of scalp, face, and neck infections, as well as tinea corporis in children. <i>T. tonsurans</i> incidence significantly increased in adults and became the most frequent agent of upper-body tinea corporis by 2022. These findings highlight a shift in pathogen distribution, with <i>T. tonsurans</i> emerging as the leading cause of upper-body skin infections, underscoring the need for targeted prevention strategies and further investigation of its transmission routes.https://www.mdpi.com/2309-608X/11/4/320cutaneous fungal infectiondermatophytes<i>Trichophyton rubrum</i><i>Trichophyton tonsurans</i> |
| spellingShingle | Eran Galili Auriella Taieb Avner Shemer Gil Leor Anna Lyakhovitsky Aviv Barzilai Sharon Baum Epidemiology and Trends of Cutaneous Fungal Infections (2019–2022) in Israel: A Single Tertiary-Center Study Journal of Fungi cutaneous fungal infection dermatophytes <i>Trichophyton rubrum</i> <i>Trichophyton tonsurans</i> |
| title | Epidemiology and Trends of Cutaneous Fungal Infections (2019–2022) in Israel: A Single Tertiary-Center Study |
| title_full | Epidemiology and Trends of Cutaneous Fungal Infections (2019–2022) in Israel: A Single Tertiary-Center Study |
| title_fullStr | Epidemiology and Trends of Cutaneous Fungal Infections (2019–2022) in Israel: A Single Tertiary-Center Study |
| title_full_unstemmed | Epidemiology and Trends of Cutaneous Fungal Infections (2019–2022) in Israel: A Single Tertiary-Center Study |
| title_short | Epidemiology and Trends of Cutaneous Fungal Infections (2019–2022) in Israel: A Single Tertiary-Center Study |
| title_sort | epidemiology and trends of cutaneous fungal infections 2019 2022 in israel a single tertiary center study |
| topic | cutaneous fungal infection dermatophytes <i>Trichophyton rubrum</i> <i>Trichophyton tonsurans</i> |
| url | https://www.mdpi.com/2309-608X/11/4/320 |
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