Predictors of Weight Change in Male HIV-Positive Injection Drug Users Initiating Antiretroviral Therapy in Hanoi, Vietnam
We examined clinical and nutritional predictors of weight change over two consecutive 6-month intervals among 99 HIV-positive male injection drug users initiating antiretroviral therapy (ART) in Hanoi, Vietnam. The average weight gain was 3.1 ± 4.8 kg in the first six months after A...
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| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2011-01-01
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| Series: | AIDS Research and Treatment |
| Online Access: | http://dx.doi.org/10.1155/2011/890308 |
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| author | Alice M. Tang Heidi B. Sheehan Michael R. Jordan Dang Van Duong Norma Terrin Kimberly Dong Trinh Thi Minh Lien Nguyen Vu Trung Christine A. Wanke Nguyen Duc Hien |
| author_facet | Alice M. Tang Heidi B. Sheehan Michael R. Jordan Dang Van Duong Norma Terrin Kimberly Dong Trinh Thi Minh Lien Nguyen Vu Trung Christine A. Wanke Nguyen Duc Hien |
| author_sort | Alice M. Tang |
| collection | DOAJ |
| description | We examined clinical and nutritional predictors of weight change over two consecutive 6-month intervals among 99 HIV-positive male injection drug users initiating antiretroviral therapy (ART) in Hanoi, Vietnam. The average weight gain was
3.1 ± 4.8 kg in the first six months after ART and
0.8 ± 3.0 kg in the following six months. Predictors of weight change differed by interval. In the first interval, CD4 < 200 cells/μL, excellent/very good adherence to ART, bothersome nausea, and liquid supplement use were all associated with positive weight changes. Moderate to heavy alcohol use and tobacco smoking were associated with negative weight changes. In the second interval, having a CD4 count <200 cells/μL at the beginning of the interval and tobacco smoking were the only significant predictors and both were associated with negative weight changes. We identified several potential areas for interventions to promote weight gain immediately after starting ART in this population. Studies are needed to determine whether improving weight prior to, or at, ART initiation will result in improved outcomes on ART. |
| format | Article |
| id | doaj-art-6ddf9d4a0f774e048aa5ef500003cd4e |
| institution | Kabale University |
| issn | 2090-1240 2090-1259 |
| language | English |
| publishDate | 2011-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | AIDS Research and Treatment |
| spelling | doaj-art-6ddf9d4a0f774e048aa5ef500003cd4e2025-02-03T01:20:51ZengWileyAIDS Research and Treatment2090-12402090-12592011-01-01201110.1155/2011/890308890308Predictors of Weight Change in Male HIV-Positive Injection Drug Users Initiating Antiretroviral Therapy in Hanoi, VietnamAlice M. Tang0Heidi B. Sheehan1Michael R. Jordan2Dang Van Duong3Norma Terrin4Kimberly Dong5Trinh Thi Minh Lien6Nguyen Vu Trung7Christine A. Wanke8Nguyen Duc Hien9Department of Public Health and Community Medicine, Tufts University School of Medicine, Jaharis 265, Boston, MA 02111, USADepartment of Public Health and Community Medicine, Tufts University School of Medicine, Jaharis 265, Boston, MA 02111, USADepartment of Public Health and Community Medicine, Tufts University School of Medicine, Jaharis 265, Boston, MA 02111, USABach Mai Hospital, Center of Pathology, Hanoi, VietnamDepartment of Medicine, Tufts University School of Medicine, Boston, MA 02111, USADepartment of Public Health and Community Medicine, Tufts University School of Medicine, Jaharis 265, Boston, MA 02111, USANational Hospital of Tropical Diseases, Hanoi, VietnamNational Hospital of Tropical Diseases, Hanoi, VietnamDepartment of Public Health and Community Medicine, Tufts University School of Medicine, Jaharis 265, Boston, MA 02111, USANational Hospital of Tropical Diseases, Hanoi, VietnamWe examined clinical and nutritional predictors of weight change over two consecutive 6-month intervals among 99 HIV-positive male injection drug users initiating antiretroviral therapy (ART) in Hanoi, Vietnam. The average weight gain was 3.1 ± 4.8 kg in the first six months after ART and 0.8 ± 3.0 kg in the following six months. Predictors of weight change differed by interval. In the first interval, CD4 < 200 cells/μL, excellent/very good adherence to ART, bothersome nausea, and liquid supplement use were all associated with positive weight changes. Moderate to heavy alcohol use and tobacco smoking were associated with negative weight changes. In the second interval, having a CD4 count <200 cells/μL at the beginning of the interval and tobacco smoking were the only significant predictors and both were associated with negative weight changes. We identified several potential areas for interventions to promote weight gain immediately after starting ART in this population. Studies are needed to determine whether improving weight prior to, or at, ART initiation will result in improved outcomes on ART.http://dx.doi.org/10.1155/2011/890308 |
| spellingShingle | Alice M. Tang Heidi B. Sheehan Michael R. Jordan Dang Van Duong Norma Terrin Kimberly Dong Trinh Thi Minh Lien Nguyen Vu Trung Christine A. Wanke Nguyen Duc Hien Predictors of Weight Change in Male HIV-Positive Injection Drug Users Initiating Antiretroviral Therapy in Hanoi, Vietnam AIDS Research and Treatment |
| title | Predictors of Weight Change in Male HIV-Positive Injection Drug Users Initiating Antiretroviral Therapy in Hanoi, Vietnam |
| title_full | Predictors of Weight Change in Male HIV-Positive Injection Drug Users Initiating Antiretroviral Therapy in Hanoi, Vietnam |
| title_fullStr | Predictors of Weight Change in Male HIV-Positive Injection Drug Users Initiating Antiretroviral Therapy in Hanoi, Vietnam |
| title_full_unstemmed | Predictors of Weight Change in Male HIV-Positive Injection Drug Users Initiating Antiretroviral Therapy in Hanoi, Vietnam |
| title_short | Predictors of Weight Change in Male HIV-Positive Injection Drug Users Initiating Antiretroviral Therapy in Hanoi, Vietnam |
| title_sort | predictors of weight change in male hiv positive injection drug users initiating antiretroviral therapy in hanoi vietnam |
| url | http://dx.doi.org/10.1155/2011/890308 |
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